Synaptic inhibition and the control of excitability in the rodent piriform cortex

啮齿动物梨状皮层突触抑制和兴奋性控制

• 批准号: nhmrc : 471413
• 负责人: Prof John Bekkers
• 金额: $ 30.66万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/synaptic-inhibition-control-piriform-cortex/95893
• 关键词: Synaptic; inhibition; control; excitability; rodent

We are studying the properties of neurons (nerve cells) and brain circuits that enable mammals to recognise and remember odours. Our experiments will focus on neurons in the odour-processing region of the cerebral cortex of mice. This work will answer fundamental questions about how the brain interprets sensory inputs in order to build a coherent picture of the external world. Our findings will also provide a deeper understanding of the causes of epilepsy, leading to improved treatments.

我们正在研究神经元（神经细胞）和大脑回路的特性，这些特性使哺乳动物能够识别和记住气味。我们的实验将集中在老鼠大脑皮层的气味处理区域的神经元上。这项工作将回答有关大脑如何解释感官输入的基本问题，以建立外部世界的连贯画面。我们的研究结果还将提供对癫痫病因的更深入了解，从而改善治疗方法。