Developing a network model of caloric restriction in the mouse

开发小鼠热量限制的网络模型

• 批准号: BB/J020028/1
• 负责人: John Speakman
• 金额: $ 2.91万
• 依托单位: University of Aberdeen
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2012
• 资助国家: 英国
• 起止时间: 2012 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FJ020028%2F1
• 关键词: Developing; network; model; caloric; restriction

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

目前GtR中并没有所有资助研究的摘要。这通常是因为在提交提案时不需要摘要，但也可能是因为摘要中包含个人详细信息等敏感信息。

项目成果

The effects of graded levels of calorie restriction: IX. Global metabolomic screen reveals modulation of carnitines, sphingolipids and bile acids in the liver of C57BL/6 mice.

• DOI: 10.1111/acel.12570
• 发表时间: 2017-06
• 期刊: Aging cell
• 影响因子: 7.8
• 作者: Green CL;Mitchell SE;Derous D;Wang Y;Chen L;Han JJ;Promislow DEL;Lusseau D;Douglas A;Speakman JR
• 通讯作者: Speakman JR

The effects of graded caloric restriction: XII. Comparison of mouse to human impact on cellular senescence in the colon.

• DOI: 10.1111/acel.12746
• 发表时间: 2018-06
• 期刊: Aging cell
• 影响因子: 7.8
• 作者: Fontana L;Mitchell SE;Wang B;Tosti V;van Vliet T;Veronese N;Bertozzi B;Early DS;Maissan P;Speakman JR;Demaria M
• 通讯作者: Demaria M

The effects of graded levels of calorie restriction: XI. Evaluation of the main hypotheses underpinning the life extension effects of CR using the hepatic transcriptome.

• DOI: 10.18632/aging.101269
• 发表时间: 2017-07-31
• 期刊: Aging
• 作者: Derous D;Mitchell SE;Wang L;Green CL;Wang Y;Chen L;Han JJ;Promislow DEL;Lusseau D;Douglas A;Speakman JR
• 通讯作者: Speakman JR

The effects of graded levels of calorie restriction: VI. Impact of short-term graded calorie restriction on transcriptomic responses of the hypothalamic hunger and circadian signaling pathways.

卡路里限制的分级水平的影响：vi。短期渐变卡路里限制对下丘脑饥饿和昼夜节律信号通路的转录组反应的影响。

• DOI: 10.18632/aging.100895
• 发表时间: 2016-04
• 期刊: Aging
• 作者: Derous D;Mitchell SE;Green CL;Chen L;Han JD;Wang Y;Promislow DE;Lusseau D;Speakman JR;Douglas A
• 通讯作者: Douglas A

The Effects of Graded Levels of Calorie Restriction: XIII. Global Metabolomics Screen Reveals Graded Changes in Circulating Amino Acids, Vitamins, and Bile Acids in the Plasma of C57BL/6 Mice.

• DOI: 10.1093/gerona/gly058
• 发表时间: 2019-01-01
• 期刊: The journals of gerontology. Series A, Biological sciences and medical sciences
• 作者: Green CL;Soltow QA;Mitchell SE;Derous D;Wang Y;Chen L;Han JJ;Promislow DEL;Lusseau D;Douglas A;Jones DP;Speakman JR
• 通讯作者: Speakman JR