SECRETION OF TRH AND OTHER NEURAL PEPTIDES

这项研究项目涉及到调节分泌的因素和 促甲状腺激素释放激素及其相关下丘脑的功能 从弥漫性神经内分泌系统释放激素和神经肽 脊椎动物物种，包括人类。生理刺激的影响， 神经递质、内分泌状态等因素对TRH分泌的影响 使用各种体内和体外技术进行检查。 TRH的解剖和系统发育分布的功能意义， 促黄体生成素释放激素(LH-RH)和其他促垂体激素 将对因子和神经肽进行研究。实验正在进行中 利用各种化学和免疫学技术来表征 这些神经肽在神经细胞和非神经细胞组织中的性质 不同的物种。

This research project is concerned with the factors regulating the secretion and function of thyrotrophin releasing hormone (TRH) and other related hypothalamic releasing hormones and neural peptides from the diffuse neuroendocrine system of vertebrate species, including man. The influence of physiologic stimuli, neurotransmitters, endocrine status and other factors on TRH secretion will be examined using a variety of in vivo and in vitro techniques. The functional implication of the anatomic and phylogenetic distribution of TRH, luteinizing hormone releasing hormone (LH-RH) and other hypophysiotrophic factors and neural peptides will be investigated. Experiments are being undertaken utilizing various chemical and immunologic techniques to characterize the nature of these neural peptides in neuronal and non-neuronal tissues of different species.