Control of early embryogenesis by extra-embryonic peptides

胚胎外肽对早期胚胎发生的控制

• 批准号: BB/L003023/1
• 负责人: Jose Gutierrez-Marcos
• 金额: $ 56.95万
• 依托单位: University of Warwick
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2014
• 资助国家: 英国
• 起止时间: 2014 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FL003023%2F1
• 关键词: Control; early; embryogenesis; extra; embryonic

Like animals, plants use asymmetric cell divisions to create pattern and diversity. However, how plants specify and carry out asymmetric divisions is not yet understood. This proposal focuses on uncovering the role of intercellular communication as a mechanism driving asymmetric division of the zygote in plants. We have uncovered a group of peptides expressed in embryo surrounding cells that regulate the early divisions of the zygote. We will use these findings to identify novel components to the network of genes and proteins that are involved in regulating early embryo development and patterning. Through this work we will uncover the molecular processes that allow surrounding tissues to coordinate the development of plant embryos.

像动物一样，植物利用不对称的细胞分裂来创造图案和多样性。然而，植物如何指定和执行不对称分裂尚不清楚。本研究的重点是揭示细胞间通讯在植物合子不对称分裂中的作用。我们发现了一组在胚胎周围细胞中表达的肽，这些细胞调节着受精卵的早期分裂。我们将利用这些发现来识别参与调节早期胚胎发育和模式的基因和蛋白质网络的新成分。通过这项工作，我们将揭示使周围组织协调植物胚胎发育的分子过程。

项目成果

A new role for histone demethylases in the maintenance of plant genome integrity.

• DOI: 10.7554/elife.58533
• 发表时间: 2020-10-27
• 期刊: eLife
• 影响因子: 7.7
• 作者: Antunez-Sanchez J;Naish M;Ramirez-Prado JS;Ohno S;Huang Y;Dawson A;Opassathian K;Manza-Mianza D;Ariel F;Raynaud C;Wibowo A;Daron J;Ueda M;Latrasse D;Slotkin RK;Weigel D;Benhamed M;Gutierrez-Marcos J
• 通讯作者: Gutierrez-Marcos J

A Novel Signaling Pathway Required for Arabidopsis Endodermal Root Organization Shapes the Rhizosphere Microbiome.

• DOI: 10.1093/pcp/pcaa170
• 发表时间: 2021-05-11
• 期刊: Plant & cell physiology
• 影响因子: 4.9
• 作者: Durr J;Reyt G;Spaepen S;Hilton S;Meehan C;Qi W;Kamiya T;Flis P;Dickinson HG;Feher A;Shivshankar U;Pavagadhi S;Swarup S;Salt D;Bending GD;Gutierrez-Marcos J
• 通讯作者: Gutierrez-Marcos J

Specific chromatin changes mark lateral organ founder cells in the Arabidopsis inflorescence meristem

• DOI: 10.1093/jxb/erz181
• 发表时间: 2019-08-01
• 期刊: JOURNAL OF EXPERIMENTAL BOTANY
• 影响因子: 6.9
• 作者: Frerichs, Anneke;Engelhorn, Julia;Werr, Wolfgang
• 通讯作者: Werr, Wolfgang

A transposon surveillance mechanism that safeguards plant male fertility during stress

• DOI: 10.1038/s41477-020-00818-5
• 发表时间: 2021-01-04
• 期刊: NATURE PLANTS
• 影响因子: 18
• 作者: Lee, Yang-Seok;Maple, Robert;Gutierrez-Marcos, Jose
• 通讯作者: Gutierrez-Marcos, Jose