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Using a Designer Receptor Exclusively Activated by Designer Drug to define the role of short chain fatty acids in metabolic disease and inflammation

Using a Designer Receptor Exclusively Activated by Designer Drug to define the role of short chain fatty acids in metabolic disease and inflammation
使用由设计药物独家激活的设计受体来定义短链脂肪酸在代谢疾病和炎症中的作用
批准号:
BB/L02781X/2
负责人:
Andrew Tobin
金额:
$40.69万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2017
资助国家:
英国
项目状态:
已结题
起止时间:
2017 至 --

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中文摘要
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英文摘要
Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.
期刊论文(5)
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会议论文
Chemogenetics defines a short-chain fatty acid receptor gut-brain axis.
化学遗传学定义了短链脂肪酸受体肠脑轴。
DOI: 10.7554/elife.73777
发表时间: 2022-03-01
期刊: eLife
影响因子: 7.7
作者: [Barki N, Bolognini D, Börjesson U, Jenkins L, Riddell J, Hughes DI, Ulven T, Hudson BD, Ulven ER, Dekker N, Tobin AB, Milligan G]
通讯作者: Milligan G
DOI: 10.1016/j.tips.2017.06.006
发表时间: 2017-09
期刊: Trends in pharmacological sciences
影响因子: 13.8
作者: [Milligan G, Alvarez-Curto E, Hudson BD, Prihandoko R, Tobin AB]
通讯作者: Tobin AB
DOI: 10.1021/acsptsci.0c00079
发表时间: 2020-10-09
期刊: ACS pharmacology & translational science
影响因子: --
作者: [Quon T, Lin LC, Ganguly A, Tobin AB, Milligan G]
通讯作者: Milligan G
MICA: Determining the therapeutic potential of targeting the free fatty acid receptors FFA1 and FFA4 in human lung inflammatory disease
  • 批准号:
    MR/X010198/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $134.27万
  • 财政年份:
    2023
  • 负责人:
    Andrew Tobin
  • 依托单位:
Development of next generation anti-malarials targeting the essential parasite protein kinase PfCLK3
  • 批准号:
    MR/T030569/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $87.7万
  • 财政年份:
    2020
  • 负责人:
    Andrew Tobin
  • 依托单位:
MICA: Defining the functional modes of action, and therapeutic potential of targeting, the free fatty acid receptor FFA4 in the lung.
  • 批准号:
    MR/R00305X/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $122.14万
  • 财政年份:
    2018
  • 负责人:
    Andrew Tobin
  • 依托单位:
Defining the functional roles of the enigmatic G protein-coupled receptor GPR35
  • 批准号:
    BB/P00069X/1
  • 项目类别:
    Research Grant
  • 资助金额:
    $76.81万
  • 财政年份:
    2017
  • 负责人:
    Andrew Tobin
  • 依托单位:
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