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DNA Synthesis at the Norwich Research Park

DNA Synthesis at the Norwich Research Park
诺维奇研究园的 DNA 合成
批准号:
BB/M000966/1
负责人:
Mario Caccamo
金额:
$242.48万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2014
资助国家:
英国
项目状态:
已结题
起止时间:
2014 至 --

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中文摘要
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英文摘要
We propose to set up a DNA Synthesis facility at the Norwich Research Park (NRP) with the aim to support the design, generation and exploitation of high-value compounds and bioactives obtained from plants and microbes. These are areas of strength within the Norwich Research Park (NRP) which hosts a number of research institutes with strategic programmes that are recognised as international leaders, in particular in areas around the generation of novel antibiotics and other valuable secondary metabolites such as terpenes and anthocyanins. More recently the development of targeted genome editing technologies have emerged as another complementary area of strength within the NRP. The DNA synthesis facility within the NRP will also contribute to enhance the opportunities to develop computational methods in areas relevant to systems biology complementing other technology platforms within the NRP. The focus will be on the modelling of gene networks, which is placed at the interface of systems and synthetic biology.
期刊论文(10)
专著(0)
科研奖励(0)
会议论文
DOI: 10.1042/bst20160012
发表时间: 2016-06-15
期刊: Biochemical Society transactions
影响因子: 3.9
作者: [Johnson JR, D'Amore R, Thain SC, Craig T, McCue HV, Hertz-Fowler C, Hall N, Hall AJ]
通讯作者: Hall AJ
DOI: 10.1038/nbt.4263
发表时间: 2018-10-11
期刊: Nature biotechnology
影响因子: 46.9
作者: [Kahl L, Molloy J, Patron N, Matthewman C, Haseloff J, Grewal D, Johnson R, Endy D]
通讯作者: Endy D
DOI: 10.1093/nar/gkaa682
发表时间: 2020-12-02
期刊: Nucleic acids research
影响因子: 14.9
作者: [Cai YM, Kallam K, Tidd H, Gendarini G, Salzman A, Patron NJ]
通讯作者: Patron NJ
Comparison of Efficiency and Specificity of CRISPR-Associated (Cas) Nucleases in Plants: An Expanded Toolkit for Precision Genome Engineering
植物中 CRISPR 相关 (Cas) 核酸酶的效率和特异性比较:精密基因组工程的扩展工具包
DOI: 10.1101/422766
发表时间: 2018
期刊:
影响因子: --
作者: [Raitskin O]
通讯作者: Raitskin O
Open Access Block Award 2023 - National Inst of Agricultural Botany
Open Access Block Award 2022 - National Inst of Agricultural Botany
21ROMITIGATIONFUND National Institute of Agricultural Botany
An evolutionary approach to optimising synthetic apomixis in cereal crops
国内基金
海外基金
新型滤波器综合技术-直接综合技术(Direct synthesis Technique)的研究及应用
  • 批准号:
    61671111
  • 项目类别:
    面上项目
  • 资助金额:
    58.0万元
  • 批准年份:
    2016
  • 负责人:
    肖飞
  • 依托单位: