14-ATC2. Engineering resistance to disease in pigs

14-ATC2。

• 批准号: BB/M018385/1
• 负责人: Laurence Tiley
• 金额: $ 15.65万
• 依托单位: University of Cambridge
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2014
• 资助国家: 英国
• 起止时间: 2014 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FM018385%2F1
• 关键词: 14; ATC2.; Engineering; resistance; disease

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

目前GtR中并没有所有资助研究的摘要。这通常是因为在提交提案时不需要摘要，但也可能是因为摘要中包含个人详细信息等敏感信息。

项目成果

Adaptation of avian influenza virus to a swine host.

• DOI: 10.1093/ve/vex007
• 发表时间: 2017-01
• 期刊: Virus evolution
• 影响因子: 5.3
• 作者: Bourret V;Lyall J;Frost SDW;Teillaud A;Smith CA;Leclaire S;Fu J;Gandon S;Guérin JL;Tiley LS
• 通讯作者: Tiley LS

Livestock 2.0 - genome editing for fitter, healthier, and more productive farmed animals.

• DOI: 10.1186/s13059-018-1583-1
• 发表时间: 2018-11-26
• 期刊: Genome biology
• 影响因子: 12.3
• 作者: Tait-Burkard C;Doeschl-Wilson A;McGrew MJ;Archibald AL;Sang HM;Houston RD;Whitelaw CB;Watson M
• 通讯作者: Watson M

Transgenic animals resistant to infectious diseases.

• DOI: 10.20506/rst.35.1.2422
• 发表时间: 2016-04
• 期刊: Revue scientifique et technique
• 作者: L. Tiley

Precision engineering for PRRSV resistance in pigs: Macrophages from genome edited pigs lacking CD163 SRCR5 domain are fully resistant to both PRRSV genotypes while maintaining biological function.

• DOI: 10.1371/journal.ppat.1006206
• 发表时间: 2017-02
• 期刊: PLoS pathogens
• 影响因子: 6.7
• 作者: Burkard C;Lillico SG;Reid E;Jackson B;Mileham AJ;Ait-Ali T;Whitelaw CB;Archibald AL
• 通讯作者: Archibald AL

Adaptation of avian influenza virus to a swine host

禽流感病毒对猪宿主的适应

• DOI: 10.17863/cam.8659
• 发表时间: 2017
• 作者: Bourret V