DNA-directed construction of three-dimensional photosynthetic assemblies

DNA 指导构建三维光合组件

• 批准号: BB/N016378/1
• 负责人: Glenn Burley
• 金额: $ 29.02万
• 依托单位: University of Strathclyde
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2016
• 资助国家: 英国
• 起止时间: 2016 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FN016378%2F1
• 关键词: DNA; directed; construction; three; dimensional

The aim of this project is to explore a completely new way of organising light harvesting modules where they can be placed in both two and three-dimensions with nanoscale precision. We will systematically investigate how the transfer of excitation energy from one light harvesting module to the next correlates to their overall arrangement within a DNA nanostructure. Going into the third dimension will be a key aim of this proposal since this will allow the building of larger cross-sections of absorbance. Any device that aims to use solar energy must harvest the light as a first step. As such, this proposal sets out to develop a new strategy to optimise the first step in this process.

该项目的目的是探索一种全新的方式来组织光收集模块，它们可以以纳米级精度放置在二维和三维空间中。我们将系统地研究激发能量从一个光捕获模块到下一个模块的转移如何与它们在DNA纳米结构内的整体排列相关。进入第三维将是该提案的一个关键目标，因为这将允许建立更大的吸收截面。任何旨在利用太阳能的设备都必须将收集光作为第一步。因此，本提案旨在制定一项新战略，以优化这一过程的第一步。

项目成果

Structural and Kinetic Profiling of Allosteric Modulation of Duplex DNA Induced by DNA-Binding Polyamide Analogues.

DNA结合聚酰胺类似物诱导的双链DNA的变构调节的结构和动力学分析。

• DOI: 10.1002/chem.201805338
• 发表时间: 2019-02-21
• 期刊: Chemistry (Weinheim an der Bergstrasse, Germany)
• 作者: Aman K;Padroni G;Parkinson JA;Welte T;Burley GA
• 通讯作者: Burley GA

A flow platform for degradation-free CuAAC bioconjugation.

• DOI: 10.1038/s41467-018-06551-0
• 发表时间: 2018-10-01
• 期刊: Nature communications
• 影响因子: 16.6
• 作者: Hatit MZC;Reichenbach LF;Tobin JM;Vilela F;Burley GA;Watson AJB
• 通讯作者: Watson AJB