CELL BIOLOGY OF THE RETINA

视网膜的细胞生物学

• 批准号: 3255917
• 负责人: ELIO S RAVIOLA
• 金额: $ 21.39万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 1977
• 资助国家: 美国
• 起止时间: 1977-08-01 至 1987-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3255917
• 关键词: aspartate; dark adaptation; electron microscopy; freeze etching; intercellular connection; interference microscopy; ions; light adaptations; membrane reconstitution /synthesis; neural transmission; neuropharmacology; neurophysiology; retina; synaptic vesicles; tissue /cell culture; visual photoreceptor

In this project the Principal Investigator describes studies on: 1) transmitter release and synaptic vesicle membrane recycling in the photoreceptor endings of the retina using electrophysiological and morphological techniques; 2) the effects of illumination on the structure of photoreceptor outer segments using rapid freezing at 4 degrees K and electron microscopy; 3) labeling functionally active synaptic endings in the mammalian retina with ultrastructural tracers; 4) connectivity of cone cells in the turtle retina.

在本项目中，主要研究者描述了以下方面的研究：1）发射器 释放和突触囊泡膜再循环在感光体末梢的 使用电生理学和形态学技术的视网膜; 2） 光照对光感受器外节结构的影响 4 ℃快速冷冻和电镜观察; 3）功能性标记 用超微结构示踪剂观察哺乳动物视网膜中的活性突触末梢; 4） 海龟视网膜中视锥细胞的连通性。