TOXIC EFFECTS OF BENZOPYRENE ON IMMUNOCOMPETENT CELLS

苯并芘对免疫活性细胞的毒性作用

• 批准号: 3250613
• 负责人: LAWRENCE B SCHOOK
• 金额: $ 1.16万
• 依托单位: VIRGINIA COMMONWEALTH UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1984
• 资助国家: 美国
• 起止时间: 1984-05-01 至 1986-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3250613
• 关键词: B lymphocyte; T lymphocyte; antibody formation; antigen antibody reaction; autoradiography; benzopyrenes; cell cell interaction; cellular immunity; chemical aggregate; chemical carcinogenesis; cytotoxicity; drug adverse effect; electrofocusing; environmental toxicology; flow cytometry; gel electrophoresis; humoral immunity; immune complex; immune tolerance /unresponsiveness; immunodeficiency; immunofluorescence technique; immunoregulation; immunosuppression; immunosuppressive; immunotoxicity; leukocyte activation /transformation; macromolecule; macrophage; molecular site; radioimmunoassay; radionuclides; stainings; surface antigens; tissue /cell culture; toxicant interaction

项目成果

Immunomodulation by polyaromatic hydrocarbons in mice and murine cells.

多环芳烃对小鼠和鼠科动物细胞的免疫调节作用。

• 发表时间: 1986
• 期刊: Cancer research
• 影响因子: 11.2
• 作者: Blanton,RH;Lyte,M;Myers,MJ;Bick,PH
• 通讯作者: Bick,PH

Effect of in vivo administration of the carcinogen benzo(a)pyrene on interleukin-2 and interleukin-3 production.

体内施用致癌物质苯并(a)芘对白细胞介素 2 和白细胞介素 3 产生的影响。

• DOI: 10.1016/0192-0561(87)90055-5
• 发表时间: 1987
• 期刊: International journal of immunopharmacology
• 作者: Lyte,M;Blanton,RH;Myers,MJ;Bick,PH
• 通讯作者: Bick,PH

Modulation of immunocompetent cell populations by benzo[a]pyrene.

通过苯并[a]芘调节免疫活性细胞群。

• DOI: 10.1016/0041-008x(88)90126-3
• 发表时间: 1988
• 期刊: Toxicology and applied pharmacology
• 影响因子: 3.8
• 作者: Blanton,RH;Myers,MJ;Bick,PH
• 通讯作者: Bick,PH

Mechanisms of benzo(a)pyrene-induced modulation of antigen presentation.

苯并（a）芘诱导的抗原呈递调节机制。

• 发表时间: 1987
• 期刊: The Journal of pharmacology and experimental therapeutics
• 作者: Myers,MJ;Schook,LB;Bick,PH
• 通讯作者: Bick,PH