THE CHEMISTRY OF NATURAL PRODUCTS
THE CHEMISTRY OF NATURAL PRODUCTS
批准号:
3268041
负责人:
GEORGE H BUCHI
金额:
$30.45万
依托单位国家:
美国
项目类别:
财政年份:
1977
资助国家:
美国
项目状态:
已结题
起止时间:
1977-04-01 至 1987-03-31
中文摘要
本文介绍了一种合成海洋产品monobromo和dibromphakellin的方法,
生物遗传模式路线。 在一项相关的研究中,
研究麻痹性贝类毒素石房蛤毒素。 米孕酚A厂
不属于类固醇的雌激素正在合成。 麦角酸
一些相关化合物是多种药物的结构单元。 一
麦角酸和相关麦角林的生物遗传模式合成
正在开发中。 人们正试图将双萘醌
涉及含有以下基本环结构的分子内羟醛产物:
萘环素类抗生素 一个关于生物起源的推测性方案
thiaspirane生物碱正在实验测试中。 一个新
将合成由寄生曲霉产生的抗生素。
英文摘要
The marine products monobromo and dibromphakellin will be synthesized by a
biogenetically patterned route. In a related study a synthesis of the
paralytic shellfish poison saxitoxin is investigated. Mirestrol a plant
estrogen not belonging to the steriods is being synthesized. Lysergic acid
and some related compounds are structural units of several drugs. A
biogenetically patterned synthesis of lysergic acid and related ergolines
is being developed. Attempts are being made to convert bisnaphthoquinones
to intramolecular aldol products containing the basic ring structures of
the naphthocyclinone antibiotics. A speculative scheme for the biogenesis
of the thiaspirane alkaloids is being tested experimentally. A new
antibiotic produced by Aspergillus parasiticus will be synthesized.
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会议论文
CARCINOGENESIS AND DRUG DEVELOPMENT
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批准号:3532486
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项目类别:
-
资助金额:$33.03万
-
财政年份:1980
-
负责人:GEORGE H BUCHI
-
依托单位:
CARCINOGENESIS AND DRUG DEVELOPMENT
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批准号:3532487
-
项目类别:
-
资助金额:$34.6万
-
财政年份:1980
-
负责人:GEORGE H BUCHI
-
依托单位:
CARCINOGENESIS AND DRUG DEVELOPMENT
-
批准号:3532488
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项目类别:
-
资助金额:$26.6万
-
财政年份:1980
-
负责人:GEORGE H BUCHI
-
依托单位:
CARCINOGENESIS AND DRUG DEVELOPMENT
-
批准号:3532482
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项目类别:
-
资助金额:$36.3万
-
财政年份:1980
-
负责人:GEORGE H BUCHI
-
依托单位:
CARCINOGENESIS AND DRUG DEVELOPMENT
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批准号:3532485
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项目类别:
-
资助金额:$30.98万
-
财政年份:1980
-
负责人:GEORGE H BUCHI
-
依托单位:
THE CHEMISTRY OF NATURAL PRODUCTS
-
批准号:3268043
-
项目类别:
-
资助金额:$23.29万
-
财政年份:1977
-
负责人:GEORGE H BUCHI
-
依托单位:
THE CHEMISTRY OF NATURAL PRODUCTS
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批准号:3268040
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项目类别:
-
资助金额:$28.15万
-
财政年份:1977
-
负责人:GEORGE H BUCHI
-
依托单位:
THE CHEMISTRY OF NATURAL PRODUCTS
-
批准号:3268039
-
项目类别:
-
资助金额:$17.43万
-
财政年份:1977
-
负责人:GEORGE H BUCHI
-
依托单位:
THE CHEMISTRY OF NATURAL PRODUCTS
-
批准号:3268042
-
项目类别:
-
资助金额:$18.57万
-
财政年份:1977
-
负责人:GEORGE H BUCHI
-
依托单位:
海外基金