21-BBSRC/NSF-BIO Molecular dissection of symbiosis regulation of plant immunity

21-BBSRC/NSF-BIO 植物免疫共生调控的分子解剖

• 批准号: BB/X011933/1
• 负责人: Giles Oldroyd
• 金额: $ 78.91万
• 依托单位: University of Cambridge
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FX011933%2F1
• 关键词: 21; BBSRC; NSF; BIO; Molecular

Food production is currently achieved through unsustainable farming practices including the application of large amounts of inorganic fertilizers to provide essential nutrients for crop growth. This has led to a loss of biodiversity, degradation of land quality, and environmental pollution. Plants naturally associate with a wide variety of microorganisms, including some beneficial microbes that can infect plant roots to establish mutualistic relationships called symbioses. Among the symbiotic interactions are those between nitrogen-fixing rhizobial bacteria and legumes, as well as arbuscular mycorrhizal fungi (AMF) with most land plants. To establish these symbioses, plants must recognize these microbes as friends, not foes, and adjust their development and cellular physiology to accommodate microbial infection. Symbiosis also necessitates the avoidance of immunity processes, either through action by the microbes or intentional suppression by the plant. In this proposal we develop our understanding of how plant recognition of symbionts interferes with immunity processes in the plant cell, to ensure that the invading microorganisms are not rejected by the immunity processes, but instead are welcomed as symbionts.

目前，粮食生产是通过不可持续的耕作方法实现的，包括施用大量无机肥料，为作物生长提供必要的营养。这导致生物多样性丧失、土地质量退化和环境污染。植物自然地与各种各样的微生物相关联，包括一些有益的微生物，它们可以感染植物根部以建立称为共生的互利关系。固氮根瘤菌与豆科植物，以及丛枝菌根真菌（AMF）与大多数陆地植物之间的共生相互作用。为了建立这些共生关系，植物必须将这些微生物视为朋友，而不是敌人，并调整它们的发育和细胞生理学以适应微生物感染。共生还需要避免免疫过程，无论是通过微生物的作用还是植物的故意抑制。在这个提议中，我们发展了我们对植物识别共生体如何干扰植物细胞中的免疫过程的理解，以确保入侵的微生物不会被免疫过程拒绝，而是作为共生体受到欢迎。

项目成果

Symbiotic regulation: How plants seek salvation in starvation.

共生调节：植物如何在饥饿中寻求拯救。

• DOI: 10.1016/j.cub.2021.11.059
• 发表时间: 2022
• 期刊: CB
• 作者: Jarratt-Barnham E

Dancing to a different tune, can we switch from chemical to biological nitrogen fixation for sustainable food security?

为了可持续的粮食安全，我们能否换一种方式从化学固氮转向生物固氮？

• DOI: 10.1371/journal.pbio.3001982
• 发表时间: 2023-03
• 期刊: PLoS biology
• 影响因子: 9.8