Mechanism of AMPK activation by drugs and metabolites

药物和代谢物激活 AMPK 的机制

• 批准号: DP170101196
• 负责人: Prof Bruce Kemp
• 金额: $ 24.94万
• 依托单位: Australian Catholic University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP170101196
• 关键词: Mechanism; AMPK; activation; drugs; metabolites

This project aims to identify the molecular basis of activation mechanisms in the AMP-activated protein kinase (AMPK), an enzyme that regulates burning and storage of fuels such as fat and sugars, autophagy and controls appetite and energy expenditure. This project expects to provide insights into how energy metabolism and physiological functions are linked.

该项目旨在确定AMP激活蛋白激酶（AMPK）激活机制的分子基础，AMPK是一种调节脂肪和糖等燃料的燃烧和储存，自噬以及控制食欲和能量消耗的酶。该项目旨在深入了解能量代谢和生理功能之间的联系。