Role of AMPK Signaling in Metabolic Control During Exercise

AMPK 信号传导在运动期间代谢控制中的作用

• 批准号: nhmrc : 1028254
• 负责人: Prof Bruce Kemp
• 金额: $ 37.76万
• 依托单位: St. Vincent's Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/role-ampk-signaling-control-exercise/110619
• 关键词: Role; AMPK; Signaling; Metabolic; Control

It is well recognized that sedentary life styles are associated with increased incidence of obesity, Type 2 diabetes and atherosclerotic cardiovascular disease. The medical, social and financial costs of these diseases are growing rapidly and represent a major health care challenge. Exercise is beneficial for maintaining health in patients at risk of developing these diseases and for this reason we are interested in understanding how exercise capacity is regulated.

众所周知，久坐不动的生活方式与肥胖、2型糖尿病和动脉粥样硬化性心血管疾病的发病率增加有关。这些疾病的医疗、社会和财政成本正在迅速增长，对卫生保健构成重大挑战。运动对有患病风险的病人保持健康是有益的，因此我们有兴趣了解运动能力是如何调节的。