Regulation of AMPK enzyme by xenobiotics and a-subunit phosphorylation

异生素和 a 亚基磷酸化对 AMPK 酶的调节

• 批准号: DP130104548
• 负责人: Prof Bruce Kemp
• 金额: $ 25.96万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP130104548
• 关键词: Regulation; AMPK; enzyme; xenobiotics; subunit

Living cells balance energy production and consumption in order to survive. An enzyme AMPK regulates burning and storage of fuels such as fat and sugars and mediates control of appetite and energy expenditure. This project will advance understandings of the regulation of AMPK and explain how some natural products modulate metabolism.

活细胞为了生存而平衡能量的产生和消耗。 AMPK 酶调节脂肪和糖等燃料的燃烧和储存，并调节食欲和能量消耗的控制。该项目将加深对 AMPK 调节的理解，并解释一些天然产物如何调节新陈代谢。