Understanding the importance of lipid metabolism in mediating the anti-diabetic effects of metformin
Understanding the importance of lipid metabolism in mediating the anti-diabetic effects of metformin
批准号:
nhmrc : 1011486
负责人:
Prof Bruce Kemp
金额:
$37.07万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2011
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2011-01-01 至 2013-12-31
中文摘要
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英文摘要
Obesity is a major cause of adult onset Type 2 diabetes. This project is investigating the mechanism of action of the glucose lowering drug metformin on fat metabolism. We are investigating whether the regulation of two enzymes, involve in fat synthesis and the burning of fat respectively that are important for metformin�s action. Through this research we hope to improve on the treatment of Type 2 diabetes and cardiovascular disease.
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Mechanism of AMPK activation by drugs and metabolites
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批准号:DP170101196
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项目类别:Discovery Projects
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资助金额:$24.94万
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财政年份:2017
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负责人:Prof Bruce Kemp
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依托单位:
Regulating Metabolism: AMPK
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批准号:nhmrc : 1078752
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项目类别:Research Fellowships
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资助金额:$58.26万
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财政年份:2015
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负责人:Prof Bruce Kemp
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依托单位:
Regulating Metabolism: AMPK
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批准号:nhmrc : GNT1078752
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项目类别:Research Fellowships
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资助金额:$83.69万
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财政年份:2015
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负责人:Prof Bruce Kemp
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依托单位:
Regulation of AMPK enzyme by xenobiotics and a-subunit phosphorylation
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批准号:DP130104548
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项目类别:Discovery Projects
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资助金额:$25.96万
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财政年份:2013
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负责人:Prof Bruce Kemp
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依托单位:
Role of AMPK Signaling in Metabolic Control During Exercise
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批准号:nhmrc : 1028254
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项目类别:Project Grants
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资助金额:$37.76万
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财政年份:2012
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负责人:Prof Bruce Kemp
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依托单位:
Systems therapeutics for metabolism: AMPK isoform specific drugs
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批准号:DP1092675
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项目类别:Discovery Projects
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资助金额:$24.72万
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财政年份:2010
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负责人:Prof Bruce Kemp
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依托单位:
Research Fellowship - Grant ID:345426
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批准号:nhmrc : 345426
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项目类别:NHMRC Research Fellowships
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资助金额:$10.22万
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财政年份:2009
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负责人:Prof Bruce Kemp
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依托单位:
Phosphoproteomics: Metabolic and Exercise Signalling Markers for Sedentary and Trained Individuals
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批准号:nhmrc : 395522
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项目类别:NHMRC Strategic Awards
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资助金额:$81.52万
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财政年份:2006
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负责人:Prof Bruce Kemp
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依托单位:
Coordinating energy metabolism to enhance exercise capacity
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批准号:DP0556024
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项目类别:Discovery Projects
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资助金额:$63.03万
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财政年份:2005
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负责人:Prof Bruce Kemp
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依托单位:
How organisms coordinate energy supply and demand
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批准号:FF0348748
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项目类别:Federation Fellowships
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资助金额:$103.35万
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财政年份:2004
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负责人:Prof Bruce Kemp
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依托单位:
Physiological effects of manipulating AMPK signalling genes
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批准号:nhmrc : 296212
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项目类别:NHMRC Project Grants
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资助金额:$25.16万
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财政年份:2004
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负责人:Prof Bruce Kemp
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依托单位:
Structure and Function of the AMP-activated protein kinase
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批准号:DP0212018
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项目类别:Discovery Projects
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资助金额:$25.56万
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财政年份:2002
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负责人:Prof Bruce Kemp
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依托单位:
Physiological effects of manipulating AMP-activated kinase genes
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批准号:nhmrc : 156713
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项目类别:NHMRC Project Grants
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资助金额:$23.41万
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财政年份:2001
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负责人:Prof Bruce Kemp
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依托单位:
IT mass spectrotry computing network
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批准号:nhmrc : 1600
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项目类别:NHMRC Infrastructure Grants
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资助金额:$1.07万
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财政年份:2000
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负责人:Prof Bruce Kemp
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依托单位:
REGULATION OF PROTEIN KINASES AND THEIR SUBSTRATES
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批准号:nhmrc : 124000
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项目类别:NHMRC Project Grants
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资助金额:$86.43万
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财政年份:2000
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负责人:Prof Bruce Kemp
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依托单位:
国内基金
海外基金
体数据表达与绘制的新方法研究
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批准号:61170206
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项目类别:面上项目
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资助金额:55.0万元
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批准年份:2011
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负责人:周秉锋
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依托单位: