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Understanding the importance of lipid metabolism in mediating the anti-diabetic effects of metformin

Understanding the importance of lipid metabolism in mediating the anti-diabetic effects of metformin
了解脂质代谢在介导二甲双胍抗糖尿病作用中的重要性
批准号:
nhmrc : 1011486
负责人:
Prof Bruce Kemp
金额:
$37.07万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2011
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2011-01-01 至 2013-12-31

项目摘要

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中文摘要
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英文摘要
Obesity is a major cause of adult onset Type 2 diabetes. This project is investigating the mechanism of action of the glucose lowering drug metformin on fat metabolism. We are investigating whether the regulation of two enzymes, involve in fat synthesis and the burning of fat respectively that are important for metformin�s action. Through this research we hope to improve on the treatment of Type 2 diabetes and cardiovascular disease.
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会议论文
Mechanism of AMPK activation by drugs and metabolites
  • 批准号:
    DP170101196
  • 项目类别:
    Discovery Projects
  • 资助金额:
    $24.94万
  • 财政年份:
    2017
  • 负责人:
    Prof Bruce Kemp
  • 依托单位:
Regulating Metabolism: AMPK
Regulating Metabolism: AMPK
  • 批准号:
    nhmrc : GNT1078752
  • 项目类别:
    Research Fellowships
  • 资助金额:
    $83.69万
  • 财政年份:
    2015
  • 负责人:
    Prof Bruce Kemp
  • 依托单位:
Regulation of AMPK enzyme by xenobiotics and a-subunit phosphorylation
  • 批准号:
    DP130104548
  • 项目类别:
    Discovery Projects
  • 资助金额:
    $25.96万
  • 财政年份:
    2013
  • 负责人:
    Prof Bruce Kemp
  • 依托单位:
国内基金
海外基金
体数据表达与绘制的新方法研究
  • 批准号:
    61170206
  • 项目类别:
    面上项目
  • 资助金额:
    55.0万元
  • 批准年份:
    2011
  • 负责人:
    周秉锋
  • 依托单位: