CARDIOVASCULAR BEHAVIOR AND THE RELAXATION RESPONSE

这项研究计划的目标是更好地定义临床 松弛反应的应用和基础生理学 催眠反应性和交感神经系统活动。注意 将重点放在(1)催眠反应的关系上 高血压患者的血压变化与其相关 松弛响应的激发，以及这些参数与 尿MHPG测定显示脑内去甲肾上腺素水平；(2) 在松弛反应的激发和催眠反应之间 在固定工作强度下运动时的耗氧量；(3) 用血浆去甲肾上腺素水平测定交感神经系统反应性 用尿MHPG测定脑去甲肾上腺素水平的变化 它们与松弛反应的激发和它们的 与催眠反应的关系。

The objectives of this research proposal are to define better the clinical applications and underlying physiology of the relaxation response as related to hypnotic responsivity and to sympathetic nervous system activity. Attention will be focused upon (1) the relation of hypnotic responsivity of borderline hypertensive patients to their blood pressure changes associated with elicitation of the relaxation response, and the relation of these parameters to brain norepinephrine levels as indicated by urinary MHPG assay; (2) the relation between elicitation of the relaxation response and hypnotic responsivity to oxygen consumption while exercising at a fixed work intensity; (3) changes in sympathetic nervous system reactivity measured by plasma norepinpehrine levels and changes in brain norepinephrine levels as measured by urinary MHPG assays which are associated with elicitation of the relaxation response and their relation to hypnotic responsivity.