Neural circuits underlying the reinstatement of food reward-seeking

恢复食物奖励寻求的神经回路

• 批准号: DE170101384
• 负责人: Dr Zhi Yi Ong
• 金额: $ 24.14万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Early Career Researcher Award
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-03-27 至 2021-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DE170101384
• 关键词: Neural; circuits; underlying; reinstatement; food

This project aims to map out the neural circuits and mechanisms underlying the reinstatement of palatable food-seeking behaviour. Despite various dietary strategies to promote weight loss in obese/overweight individuals, the wide availability of environmental food cues can reinstate palatable food-seeking behaviours, thus negating weight loss efforts. The intended outcome of this project is a better mechanistic understanding of the reinstatement of food reward-seeking behaviour to help relieve the national economic burden of obesity and to improve the cost-effectiveness of weight loss strategies.

该项目旨在绘制恢复美味食物寻找行为背后的神经回路和机制。尽管有多种饮食策略可以促进肥胖/超重个体减肥，但环境食物线索的广泛存在可以恢复可口的食物寻找行为，从而抵消减肥努力。该项目的预期成果是更好地理解恢复食物奖励行为的机制，以帮助减轻肥胖带来的国民经济负担并提高减肥策略的成本效益。