REMOVAL/INACTIVATION OF VIRUSES IN BLOOD

血液中病毒的去除/灭活

• 批准号: 3359112
• 负责人: GIRISH N VYAS
• 金额: $ 38.14万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-07-01 至 1991-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3359112
• 关键词: Betaherpesvirinae; adsorption; antiAIDS agent; antiviral agents; antiviral antibody; blood banks; blood filtration; hepatitis B virus group; hepatitis C virus; human immunodeficiency virus 1; human tissue; immune adherence reaction; leukapheresis; monoclonal antibody; natural gene amplification; nucleic acid hybridization; nucleic acid probes; retinoate; synthetic peptide; virus DNA

National focus on the AIDS epidemic has-stimulated an urgent need to prevent our blood resources transmitting a multiplicity of blood-borne viruses (BBVs), including the human immunodeficiency virus (HIV), non-A, non-B hepatitis virus (NANBHVs), hepatitis B virus (HBV), cytomegalovirus (CMV), human T-cell leukemia virus (HTLV-I/II, variants of HIV, and several other viral agents whose importance has not been fully recognized. Assessment of adsorption for virus or chemical inactivation in the experimentally infected units of blood components and plasma products is envisaged by using HIV as a prototype in vitro cultures and viral gene detection by polymerase chain reaction (PCR).

全国对艾滋病流行的重视激发了一种迫切需要