课题基金 / 基金详情

REMOVAL/INACTIVATION OF VIRUSES IN BLOOD

REMOVAL/INACTIVATION OF VIRUSES IN BLOOD
血液中病毒的去除/灭活
批准号:
3359113
负责人:
GIRISH N VYAS
金额:
$32.49万
依托单位国家:
美国
项目类别:
财政年份:
1988
资助国家:
美国
项目状态:
已结题
起止时间:
1988-07-01 至 1992-03-31

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项目成果

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中文摘要
翻译
国家对艾滋病流行的关注-刺激了一种迫切的需求 为了防止我们的血液资源传播多种 血液传播病毒(BBV),包括人类免疫缺陷 病毒(HIV)、非甲型、非乙型肝炎病毒(NANBHV)、乙肝 病毒(乙肝病毒)、巨细胞病毒(CMV)、人T细胞白血病病毒 (HTLV-I/II,艾滋病毒的变种,以及其他几种病毒制剂,其 重要性尚未得到充分认识。 评估对病毒或化学灭活的吸附 实验感染单位的血液成分和血浆 通过使用HIV作为体外培养的原型来设想产品 用聚合酶链式反应(PCR)检测病毒基因。
英文摘要
National focus on the AIDS epidemic has-stimulated an urgent need to prevent our blood resources transmitting a multiplicity of blood-borne viruses (BBVs), including the human immunodeficiency virus (HIV), non-A, non-B hepatitis virus (NANBHVs), hepatitis B virus (HBV), cytomegalovirus (CMV), human T-cell leukemia virus (HTLV-I/II, variants of HIV, and several other viral agents whose importance has not been fully recognized. Assessment of adsorption for virus or chemical inactivation in the experimentally infected units of blood components and plasma products is envisaged by using HIV as a prototype in vitro cultures and viral gene detection by polymerase chain reaction (PCR).
期刊论文(2)
专著(0)
科研奖励(0)
会议论文
Derivation of non-infectious envelope proteins from virions isolated from plasma negative for HIV antibodies.
从 HIV 抗体阴性血浆中分离出的病毒体衍生出非感染性包膜蛋白。
DOI: 10.1016/j.biologicals.2011.11.005
发表时间: 2012
期刊: Biologicals : journal of the International Association of Biological Standardization
影响因子: --
作者: [Vyas,GirishN, Stoddart,CherylA, Killian,MScott, Brennan,ToddV, Goldberg,Tiffany, Ziman,Alyssa, Bryson,Yvonne]
通讯作者: Bryson,Yvonne
Reduction of human immunodeficiency virus-infected cells from donor blood by leukocyte filtration.
通过白细胞过滤减少供体血液中受人类免疫缺陷病毒感染的细胞。
DOI: 10.1046/j.1537-2995.1989.29589284150.x
发表时间: 1989
期刊: Transfusion
影响因子: 2.9
作者: [Rawal,BD, Busch,MP, Endow,R, Garcia-de-Lomas,J, Perkins,HA, Schwadron,R, Vyas,GN]
通讯作者: Vyas,GN
IN VITRO INACTIVATION OF VIRUSES IN BLOOD COMPONENTS
IN VITRO INACTIVATION OF VIRUSES IN BLOOD COMPONENTS
IN VITRO INACTIVATION OF VIRUSES IN BLOOD COMPONENTS
IN VITRO INACTIVATION OF VIRUSES IN BLOOD COMPONENTS
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