AFFECT, FACIAL EXPRESSION, AND BRAIN ASYMMETRY

本申请中提出的研究旨在继续我们的 研究大脑的不对称性及其与情绪和抑郁的关系。 研究将在面部表情之间的关系， 通过简短的电影片段和同时记录的大脑模式 活动 第一次会议期间将进行一项方法学实验。 本项目期间的一年，旨在验证以下程序： 从正在进行的EEG中去除肌肉紧张伪影。 实验 在面部表情的时候检查脑电图， 已经研究过的情绪。 我们会把消极情绪 一个是与退缩相关的，另一个是与接近相关的， （愤怒）为了阐明情感的基础是否 偏侧化是享乐语气或接近/回避。 面部的作用 表达有助于与情感相关的EEG不对称性 将进行研究，以更准确地说明哪些组成部分， 情绪最直接地反映在头皮记录的大脑活动中。 这 将通过比较脑电图不对称的情况下，面部 情绪的迹象和实时自我报告的测量是一致的 对比前后矛盾 区分抑郁症和抑郁症的 患者和对照组也将被探索。 学意义 将在休息期间检查EEG不对称模式中的组 条件以及对认知和情感 挑战 前额叶激活不对称性与 将在这些组中比较后部皮质区域， 并扩展了我们最近的发现，即抑郁的受试者表现出 这些区域的激活不对称性之间存在反向关系。 将探讨这些群体在情绪反应方面的差异， 确定是否诱导剂，产生一系列不同的情绪， 对照组更容易让抑郁的受试者产生悲伤。 的 当面部行为发生时， 表示存在相同的情绪，以便确定，一旦 情绪被引发，是否脑电图不对称和自我报告的模式 在这些群体中是一样的。 拟议的研究将直接有助于 理解情绪和情感障碍

The research proposed in this application is designed to continue our studies of cerebral asymmetry and its relation to emotion and depression. Studies will be conducted on the relation between facial signs of emotion elicited by brief film clips and patterns of concurrently recorded brain activity. A methodological experiment will be performed during the first year of this project period which is designed to validate a procedure for removing muscle tension artifact from the ongoing EEG. The experiments which examine EEG during facial signs of emotion will broaden the range of emotions which have been studied. We will compare a negative emotion associated with withdrawal and one more commonly associated with approach (anger) in order to shed light on whether the basis for affective lateralization is hedonic tone or approach/avoidance. The role of facial expression in contributing to the EEG asymmetries associated with affect will be studied in order to more precisely specify which components of emotion are most directly reflected in scalp recorded brain activity. This will be accomplished by comparing EEG asymmetry in situations where facial signs of emotion and a measure of real-time self-report are consistent versus inconsistent. Asymmetries which differentiate between depressed patients and controls will also be explored. Differences between these groups in patterns of EEG asymmetry will be examined during resting conditions as well as in response to both cognitive and affective challenges. Relations between activation asymmetries in anterior and posterior cortical regions will be compared in these groups to replicate and extend our recent findings which suggest that depressed subjects show inverse relations between activation asymmetries in these regions. Differences between these groups in emotional response will be explored to determine whether elicitors which produce a range of different emotions in controls are more likely to produce sadness in depressed subjects. The groups will also be compared on EEG and self-report when facial behavior indicates that the same emotion is present, in order to determine, once an emotion is elicited, whether the pattern of EEG asymmetry and self-report is the same in these groups. The proposed studies will directly contribute to understanding emotion and affective disorders.