BIOLOGICAL MECHANISMS OF TOOTH ERUPTION & ROOT

牙萌出和牙根吸收的生理过程 乳牙是颅面生长发育不可或缺的一部分。 许多异常都与这些过程有关，例如 异位的、延迟的或早熟的(特发性或药物引起的)出疹，牙齿 旋转，延迟剥落和浸没(强直)乳牙。 这些问题的治疗主要是机械性的，即通过外科手术 和/或正畸装置。然而，最近的数据揭示了新的情况 这些过程的细胞和分子方面，重点是某些 与喷发和再吸收有关的生物事件。尽管如此 事件，对局部或系统的机制知之甚少 控制这些过程的开始、进展和结束的时间 在哺乳动物身上。关于这个问题的新信息会引起所有人的兴趣 参与矿化组织新陈代谢的个人 基础研究和临床水平。 这次会议的目的是召集一群演讲者，他们是 积极研究火山喷发、再吸收及相关领域 结缔组织代谢，细胞-细胞和细胞-基质相互作用， 骨定位和骨吸收的控制机制，分子方面 牙齿发育、生长发育和伤口愈合。主要关注点 这次会议的目的是将一般生物信息与 与牙萌出和牙根吸收有关的问题，以便：(A) 将这些特定的过程与生物学中的最新技术联系起来 增长和发展及类似的相关领域；和(B)确定新的 研究的途径。观众将由大约100名受邀观众组成 根据他们的利益和贡献而挑选的人 对颅面生长发育的生物学知识和 矿化组织代谢。这个小组将由大约40人组成 成熟的研究人员和60名处于早期阶段的调查人员 他们的研究生涯。此外，约有40名研究生将 被允许加入观众席，带来了参会总人数 (包括扬声器)到170人左右。会议议事录将于 将由EBSCO媒体发布，并将分发给所有参与者 所有美国牙科学校。

The physiologic processes of tooth eruption and resorption of the roots of primary teeth are an integral part of craniofacial growth and development. A number of abnormalities are associated with these processes, such as ectopic, delayed or precocious eruption (idiopathic or drug-induced), tooth rotations, delayed exfoliation and submerged (ankylosed) primary teeth. Treatment of these problems is primarily mechanical, i.e. by surgical and/or orthodontic means. However, recent data shed new light on the cellular and molecular aspects of these processes, focusing on certain biological events associated with eruption and resorption. Despite this event, little is known about the mechanisms, local or systemic, which control the time of onset, progression and termination of these processes in mammals. New information on this subject would be of interest to all individuals involved with the metabolism of mineralized tissues on the basic research and clinical levels. The aim of this conference is to assemble a group of speakers who are conducting active research on eruption, resorption and related areas of connective tissue metabolism, cell-cell and cell-matrix interactions, control mechanisms of bone apposition and resorption, molecular aspects of odontogenesis, growth and development and wound healing. The primary focus of this conference is to integrate the general biologic information with that related to tooth eruption and root resorption, in order to: (a) correlate these specific processes with the state-of-the-art in the biology of growth and development and similar related fields; and (b) identify new avenues of research. The audience will consist of about 100 invited persons, selected on the basis of their interest in and their contributions to knowledge in the biology of craniofacial growth and development and mineralized tissue metabolism. This group will consist of about 40 established researchers and 60 investigators who are in the early stages of their research careers. In addition, about 40 postgraduate students will be allowed to join the audience, bringing the total number of participants (including speakers) to about 170. The proceedings of the conference will be published by EBSCO MEDIA and will be distributed to all participants and all U.S. dental schools.