BIOLOGICAL MECHANISMS OF TOOTH ERUPTION & ROOT

牙齿萌出和牙根吸收的生理过程 乳牙是颅面生长和发育的一个组成部分。 许多异常与这些过程相关，例如 异位、延迟或早熟萌出（特发性或药物诱导性），牙齿 旋转，延迟脱落和淹没（强直）乳牙。 这些问题的治疗主要是机械的，即通过外科手术 和/或正牙装置。 然而，最近的数据显示， 这些过程的细胞和分子方面，集中在某些 与萌出和吸收相关的生物事件。 尽管如此 事件，很少有人知道的机制，局部或系统， 控制这些过程的开始、进展和终止时间 在哺乳动物中。 关于这个问题的新资料将是所有人都感兴趣的 参与矿化组织代谢的个体 基础研究和临床水平。 本次会议的目的是召集一组发言人， 积极研究出疹、吸收和相关领域， 结缔组织代谢，细胞-细胞和细胞-基质相互作用， 骨沉积和吸收的控制机制，分子方面 牙齿发生、生长发育和伤口愈合。 主要重点 这次会议的目的是将一般生物信息与 与牙齿萌出和牙根吸收有关的问题，以便：（a） 将这些特定的过程与生物学中的最新技术联系起来， （B）确定新的 研究的途径。 观众将包括约100名受邀 根据他们的兴趣和贡献挑选的人 颅面生长发育生物学知识， 矿化组织代谢 该小组将由约40名 已建立的研究人员和60名研究人员谁是在早期阶段， 他们的研究生涯。 此外，约40名研究生将 被允许加入观众，使参与者的总人数 （包括发言人）约170人。 会议记录将 由EBSCO Media出版，并将分发给所有参与者， 所有美国牙科学校

The physiologic processes of tooth eruption and resorption of the roots of primary teeth are an integral part of craniofacial growth and development. A number of abnormalities are associated with these processes, such as ectopic, delayed or precocious eruption (idiopathic or drug-induced), tooth rotations, delayed exfoliation and submerged (ankylosed) primary teeth. Treatment of these problems is primarily mechanical, i.e. by surgical and/or orthodontic means. However, recent data shed new light on the cellular and molecular aspects of these processes, focusing on certain biological events associated with eruption and resorption. Despite this event, little is known about the mechanisms, local or systemic, which control the time of onset, progression and termination of these processes in mammals. New information on this subject would be of interest to all individuals involved with the metabolism of mineralized tissues on the basic research and clinical levels. The aim of this conference is to assemble a group of speakers who are conducting active research on eruption, resorption and related areas of connective tissue metabolism, cell-cell and cell-matrix interactions, control mechanisms of bone apposition and resorption, molecular aspects of odontogenesis, growth and development and wound healing. The primary focus of this conference is to integrate the general biologic information with that related to tooth eruption and root resorption, in order to: (a) correlate these specific processes with the state-of-the-art in the biology of growth and development and similar related fields; and (b) identify new avenues of research. The audience will consist of about 100 invited persons, selected on the basis of their interest in and their contributions to knowledge in the biology of craniofacial growth and development and mineralized tissue metabolism. This group will consist of about 40 established researchers and 60 investigators who are in the early stages of their research careers. In addition, about 40 postgraduate students will be allowed to join the audience, bringing the total number of participants (including speakers) to about 170. The proceedings of the conference will be published by EBSCO MEDIA and will be distributed to all participants and all U.S. dental schools.