Very High Intensity Single Crystal Diffractometers (VHISCD)
Very High Intensity Single Crystal Diffractometers (VHISCD)
批准号:
EP/K038869/1
负责人:
Mark Searle
金额:
$129.44万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2013
资助国家:
英国
项目状态:
已结题
起止时间:
2013 至 --
中文摘要
化学学院在诺丁汉大学是一个充满活力的,创新的国际公认的研究中心。学校在2008年RAE中排名英国第二(在剑桥和牛津之间),目前的赠款收入超过2000万英镑。我们突出的优势之一是合成化学和详细的结构表征和分析之间的密切互动。这项建议的目的正是要在这一优势的基础上再接再厉,扩大其能力和广度。 单晶X射线晶体学分析是我们所有涉及合成化学研究的生产力的基础。它对于新材料的明确表征至关重要,但也揭示了结构,性能和功能之间的关系。在许多情况下,结构数据定义了下一代目标材料,并支持其设计的优化。每年有超过1200个样品提交给学校的晶体结构设施,但许多样品太难使用我们的旧仪器进行研究-这些现在已经落后于目前可用的几代技术。我们现在正在寻找真正的重大升级,我们的仪器,利用一些令人兴奋的,最近开发的技术,包括非常明亮的实验室X射线源。
英文摘要
The School of Chemistry at The University of Nottingham is a vigorous, innovative hub for internationally-recognised research. The School was ranked 2nd in the UK (between Cambridge and Oxford) by the 2008 RAE, and current grant income exceeds £20M. One of our highlighted strengths is the close interaction between synthetic chemistry and detailed structural characterisation and analysis. This proposal is aimed squarely at building on this strength and increasing its capacity and breadth. Single crystal X-ray crystallographic analysis underpins the productivity of all our research involving synthetic chemistry. It is essential for the unambiguous characterisation of new materials, but also reveals relationships between structure, properties and function. In many cases structural data define the next generation of target materials and underpin the optimisation of their design. Over 1200 samples are submitted to the School's Crystal Structure Facility each year, but many are too difficult to study using our older instruments - these are now several technological generations behind what is currently available. We are now looking for really major upgrades to our instrumentation, by taking advantage of some exciting, recently-developed technologies including very bright laboratory X-ray sources.
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High-pressure studies of palladium and platinum thioether macrocyclic dihalide complexes.
钯和铂硫醚大环二卤化物配合物的高压研究。
DOI:
10.1107/s2052520614008786
发表时间:
2014
期刊:
Acta crystallographica Section B, Structural science, crystal engineering and materials
影响因子:
--
作者:
[Allan DR]
通讯作者:
Allan DR
The continuing development and expansion of Acta Crystallographica Section B
晶体学学报 B 部分的持续发展和扩展
DOI:
10.1107/s2052520615001663
发表时间:
2015
期刊:
Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials
影响因子:
--
作者:
[Blake A]
通讯作者:
Blake A
Two pseudohalide-bridged Cu(II) complexes bearing the anthracene moiety: Synthesis, crystal structures and catecholase-like activity
带有蒽部分的两种拟卤化物桥联的 Cu(II) 配合物:合成、晶体结构和儿茶酚酶样活性
DOI:
10.1016/j.poly.2016.08.015
发表时间:
2016
期刊:
Polyhedron
影响因子:
2.6
作者:
[Adak P]
通讯作者:
Adak P
Dilithium cyclohexanediacetate: A layered coordination polymer with non-valent hydrophobic contacts
环己烷二乙酸二锂:具有非价疏水接触的层状配位聚合物
DOI:
10.1134/s0022476614060146
发表时间:
2015
期刊:
Journal of Structural Chemistry
影响因子:
0.8
作者:
[Aliev S]
通讯作者:
Aliev S
DOI:
10.1021/jacs.6b08059
发表时间:
2016-11-16
期刊:
Journal of the American Chemical Society
影响因子:
15
作者:
[Benson O, da Silva I, Argent SP, Cabot R, Savage M, Godfrey HG, Yan Y, Parker SF, Manuel P, Lennox MJ, Mitra T, Easun TL, Lewis W, Blake AJ, Besley E, Yang S, Schröder M]
通讯作者:
Schröder M
共 8 条
Enhancing 800 MHz NMR Capabilities at Nottingham
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批准号:EP/R029768/1
-
项目类别:Research Grant
-
资助金额:$123.08万
-
财政年份:2018
-
负责人:Mark Searle
-
依托单位:
Structural role of a unique p62 UBA dimer in the regulation of signal transduction and autophagy
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批准号:BB/I011420/1
-
项目类别:Research Grant
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资助金额:$48.27万
-
财政年份:2011
-
负责人:Mark Searle
-
依托单位:
Specificity in protein-ligand recognition: characterisation of a novel conformational switch in the p62 UBA domain interaction with ubiquitin
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批准号:BB/F013663/1
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项目类别:Research Grant
-
资助金额:$42.99万
-
财政年份:2008
-
负责人:Mark Searle
-
依托单位:
海外基金