Utilising the Coordination chemistry tool-box to tackle issues ranging from Catalysis to Cancer

我们将国际公认的实验室聚集在一起，在项目上进行合作，这将促进英国与主要合作伙伴中国和日本的全球科学互动。实验室将涉及的广泛科学领域包括聚合催化、能源和癌症化学。英国合作伙伴在配位化学方面具有很高的知名度，与远东各集团的伙伴关系将使他们能够获得在英国不容易获得的最先进的设施。合作伙伴关系将i)设计能够形成具有新性能的塑料材料的新型催化剂。针对目前的堆填问题，我们也将重点研究生物可降解聚合物的形成。ii)探索金属有机框架（采用网格状3D结构的化合物）的分子结构如何影响氢气和二氧化碳等气体的储存能力。Iii)设计用于在密闭空间中分解水或进行催化的新催化剂；这种系统将使用丰富的金属而不是贵重金属。Iv)研究金属基化合物，以期发现新的抗癌药物。许多合成工作将在日本进行的分子建模指导下进行。

We are bringing together internationally recognised laboratories to collaborate on projects which will advance UK global scientific interactions with key partners, China and Japan. The broad areas of science in which the laboratories will engage are polymerization catalysis, energy and cancer chemistry. The UK partner has a high profile in coordination chemistry, and the partnerships with the groups in the Far East will enable access to state-of-the-art facilities which are not readily available in the UK.The partnerships will i) design new catalysts capable of forming plastic materials with new properties. With a view to the current landfill problems, we will also focus on the formation of biodegradable polymers. ii) probe how the molecular structure of metal organic frameworks (compounds adopting grid-like 3D structures) influence the storage capacity for gases such as hydrogen and carbon dioxide.iii) design new catalysts for spliting water or conducting cataysis in confined spaces; such systems will use abundant metals rather than precious metals.iv) investigate metal-based compounds with a view to identifying new anti-cancer agents.Much of the synthetic work will be guided by molecular modelling conducted in Japan.