课题基金 / 基金详情

Utilising the Coordination chemistry tool-box to tackle issues ranging from Catalysis to Cancer

Utilising the Coordination chemistry tool-box to tackle issues ranging from Catalysis to Cancer
利用配位化学工具箱解决从催化到癌症的各种问题
批准号:
EP/L012804/1
负责人:
Carl Redshaw
金额:
$7.29万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2014
资助国家:
英国
项目状态:
已结题
起止时间:
2014 至 --

项目摘要

项目成果

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中文摘要
翻译
我们将国际公认的实验室聚集在一起,合作开展项目,这将推动英国与中国和日本等主要合作伙伴的全球科学互动。这些实验室将从事的科学领域包括聚合催化、能源和癌症化学。英国的合作伙伴在配位化学领域具有很高的知名度,与远东集团的合作将使他们能够获得英国尚不具备的最先进的设施。合作伙伴关系将i)设计能够形成具有新特性的塑料材料的新催化剂。鉴于目前的堆填区问题,我们还将重点放在生物降解聚合物的形成上。ii)探索金属有机框架的分子结构如何(采用网格状3D结构的化合物)影响气体如氢气和二氧化碳的储存容量。iii)设计用于在受限空间中分解水或进行催化的新催化剂;这种系统将使用大量的金属而不是贵金属。iv)研究金属基化合物,以确定新的抗-大部分合成工作将由日本进行的分子建模指导。
英文摘要
We are bringing together internationally recognised laboratories to collaborate on projects which will advance UK global scientific interactions with key partners, China and Japan. The broad areas of science in which the laboratories will engage are polymerization catalysis, energy and cancer chemistry. The UK partner has a high profile in coordination chemistry, and the partnerships with the groups in the Far East will enable access to state-of-the-art facilities which are not readily available in the UK.The partnerships will i) design new catalysts capable of forming plastic materials with new properties. With a view to the current landfill problems, we will also focus on the formation of biodegradable polymers. ii) probe how the molecular structure of metal organic frameworks (compounds adopting grid-like 3D structures) influence the storage capacity for gases such as hydrogen and carbon dioxide.iii) design new catalysts for spliting water or conducting cataysis in confined spaces; such systems will use abundant metals rather than precious metals.iv) investigate metal-based compounds with a view to identifying new anti-cancer agents.Much of the synthetic work will be guided by molecular modelling conducted in Japan.
期刊论文(10)
专著(0)
科研奖励(0)
会议论文
Synthesis and Structure of 1,2-Dimethylene[2.10]metacyclophane and Its Conversion into Chiral [10]Benzenometacyclophanes
1,2-二亚甲基[2.10]偏环芳烷的合成、结构及其手性[10]苯偏环芳烷的转化
DOI: 10.1002/ejoc.201601647
发表时间: 2017
期刊: European Journal of Organic Chemistry
影响因子: 2.8
作者: [Akther T]
通讯作者: Akther T
Demethylation of 5,n-di-tert-butyl-8,n-dimethoxy[2.n]metacyclophane-1-ynes with BBr3 to afford novel [n]benzofuranophanes
用 BBr3 对 5,n-二叔丁基-8,n-二甲氧基[2.n]间环芬-1-炔进行脱甲基化,得到新型[n]苯并呋喃芬
DOI: 10.1016/j.molstruc.2016.05.054
发表时间: 2016
期刊: Journal of Molecular Structure
影响因子: 3.8
作者: [Akther T]
通讯作者: Akther T
Synthesis, Structures and Conformational Studies of 1,2-Dimethyl[2.10]metacyclophan-1-enes
1,2-二甲基[2.10]间环芳-1-烯的合成、结构和构象研究
DOI: 10.1002/slct.201600670
发表时间: 2016
期刊: ChemistrySelect
影响因子: 2.1
作者: [Akther T]
通讯作者: Akther T
Ring opening polymerization of lactides and lactones by multimetallic alkyl zinc complexes derived from the acids Ph 2 C(X)CO 2 H (X = OH, NH 2 )
通过酸 Ph 2 C(X)CO 2 H (X = OH, NH 2 ) 衍生的多金属烷基锌配合物进行丙交酯和内酯的开环聚合
DOI: 10.1039/c6ra26746g
发表时间: 2017
期刊: RSC Advances
影响因子: 3.9
作者: [Al-Khafaji Y]
通讯作者: Al-Khafaji Y
8
    Translational nanoconstructs for targeted tissue accumulation and guided surgery in cancer
    • 批准号:
      EP/X01374X/1
    • 项目类别:
      Research Grant
    • 资助金额:
      $72.96万
    • 财政年份:
      2023
    • 负责人:
      Carl Redshaw
    • 依托单位:
    Coordination chemistry approaches to societal issues: environment and health
    • 批准号:
      EP/R023816/1
    • 项目类别:
      Research Grant
    • 资助金额:
      $10.13万
    • 财政年份:
      2018
    • 负责人:
      Carl Redshaw
    • 依托单位:
    New ligand systems for metal-based catalysis: Synthesis, screening and theoretical studies
    • 批准号:
      EP/H031855/1
    • 项目类别:
      Research Grant
    • 资助金额:
      $6.54万
    • 财政年份:
      2010
    • 负责人:
      Carl Redshaw
    • 依托单位:
    Screening New families of Metal Organic Frameworks for Hydrogen Storage
    • 批准号:
      EP/F062443/1
    • 项目类别:
      Research Grant
    • 资助金额:
      $22.68万
    • 财政年份:
      2008
    • 负责人:
      Carl Redshaw
    • 依托单位:
    海外基金