EFFECTS OF BRAIN DAMAGE ON SWALLOWING AND SPEECH

语言和吞咽障碍经常在神经学上共存 受损的病人。然而，神经运动功能之间的关系 说话和吞咽的定义不是很清楚。两国之间的相互作用 在本项目中，语音和吞咽通过测试 吞咽过程中结构运动紊乱的假设可能是 从语音运动的声学相关性预测的 结构。 对三组受试者的吞咽和言语进行了研究 不同神经轴水平的持续性脑血管意外 (皮质、内囊-基底节、脑干)和一组 神经学正常的受试者。病变定位是通过 核磁共振(核磁共振)成像，并将运动模式 用视频透视成像。 舌头、腭咽和喉部运动的范围和持续时间 在说话和吞咽过程中将被量化并检查与 神经损伤的部位和运动模式。声学特性 语音产生，包括语音的持续时间和幅度 舌板辅音的释放，口腔鼻腔耦合的一个指标， 测量最大发声时间(S/z比)和音高范围 使用数字信号处理技术进行检查。这组声学 参数将用于预测选定的范围和持续时间度量 吞下去。 舌舌、腭咽和喉部吞咽的预测 动作从语音的声学关联性来看，应该提供练习 言语病理学家或吞咽治疗师有更好的工具来评估 说话和吞咽，并可能导致新的治疗方法。调查结果将 增加有关头颈部神经组织的现有知识 完成吞咽和言语产生的结构。

Speech and swallowing disorders frequently co-exist in neurologically impaired patients. However, a neuromotor relationship between the function of speech and swallowing is not well-defined. The interaction between speech and swallowing is investigated in the present project by testing the hypothesis that disordered structural movement during swallowing may be predicted from the acoustic correlates of speech movement by the same structures. Deglutition and speech are studied in 3 groups of subjects who have sustained cerebro-vascular accidents at different levels of the neuraxis (cortical, internal capsule-basal ganglia, brainstem) and a group of neurologically normal subjects. Lesion localization is determined with nuclear magnetic resonance (NMR) imaging, and movement patterns will be imaged with videofluoroscopy. Range and duration of lingua-velar, velopharyngeal, and laryngeal movements during speech and swallowing will be quantified and examined in relation to site of neurologic damage and movement patterns. Acoustic properties of speech productions, including duration and amplitude of frication at the release of a lingua-velar consonant, an index of oral nasal coupling, a measure of maximum phonation time (s/z ratio), and pitch range will be examined with digital signal processing techniques. The set of acoustic parameters will be used to predict selected range and duration measures of swallowing. Prediction of lingua-velar, velopharyngeal and laryngeal swallowing movements from the acoustic correlates of speech, should provide practicing speech pathologists or swallowing therapists with better tools to assess speech and swallowing and could lead to new treatment. The findings will add to current knowledge concerning neural organization of head and neck structures to accomplish swallowing and speech production.