Bioplastic polymers based on aromatic dicarboxylic acids derived from lignin

基于源自木质素的芳香族二羧酸的生物塑料聚合物

• 批准号: EP/M028550/1
• 负责人: Timothy Bugg
• 金额: $ 43.6万
• 依托单位: University of Warwick
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2015
• 资助国家: 英国
• 起止时间: 2015 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FM028550%2F1
• 关键词: Bioplastic; polymers; based; aromatic; dicarboxylic

Aromatic chemicals are crucial in bioplastics to convey functionality, including strength and flexibility. Currently, thesearomatic chemicals can only be sourced from fossil based inputs, limiting applications, increasing the cost andenvironmental impact. Lignin, the 2nd most abundant organic polymer in plants, is one of the few potential natural sourcesof aromatic chemicals. Building on a successful feasibility study that proved that the aromatic diacids inherent within lignincould be extracted and substituted in polyester based plastics, this project aims to demonstrate that these metabolites canbe produced in a commercially viable manner by the innovative use of modified bacteria to selectively control lignindisintegration when matched with novel chemical processes in scalable batch/continuous reactors. Larger trials will convertthe resultant kg quantities of diacids into novel block copolyesters, for evaluation in a high value global bioplastics marketof value >£150m.

芳香化学物质在生物塑料中至关重要，可以传达功能，包括强度和柔韧性。目前，硫化化学物质只能来自基于化石的投入，限制应用，增加成本和环境影响。木质素是植物中第二大最丰富的有机聚合物，是芳香化学物质的少数潜在天然来源之一。 Building on a successful feasibility study that proved that the aromatic diacids inherit within lignincould be extracted and substituted in polyester based plastics, this project aims to demonstrate that these metabolites canbe produced in a commercially viable manner by the innovative use of modified bacteria to selectively control lignindisintegration when matched with novel chemical processes in scalable batch/continuous reactors.较大的试验将将最终的二氧化氢数量转换为新型的块共聚物，以评估高价值的全球生物塑料市场，价值> 1.5亿英镑。

项目成果

Biocatalytic conversion of lignin to aromatic dicarboxylic acids in Rhodococcus jostii RHA1 by re-routing aromatic degradation pathways

• DOI: 10.1039/c5gc01347j
• 发表时间: 2015-01-01
• 期刊: GREEN CHEMISTRY
• 影响因子: 9.8
• 作者: Mycroft, Zoe;Gomis, Maria;Bugg, Timothy D. H.
• 通讯作者: Bugg, Timothy D. H.

Microbial hosts for metabolic engineering of lignin bioconversion to renewable chemicals

• DOI: 10.1016/j.rser.2021.111674
• 发表时间: 2021-10-06
• 期刊: RENEWABLE & SUSTAINABLE ENERGY REVIEWS
• 影响因子: 15.9
• 作者: Bugg, Timothy D. H.;Williamson, James J.;Alberti, Fabrizio
• 通讯作者: Alberti, Fabrizio

Metabolic engineering of Rhodococcus jostii RHA1 for production of pyridine-dicarboxylic acids from lignin.

• DOI: 10.1186/s12934-020-01504-z
• 发表时间: 2021-01-19
• 期刊: Microbial cell factories
• 影响因子: 6.4
• 作者: Spence EM;Calvo-Bado L;Mines P;Bugg TDH
• 通讯作者: Bugg TDH