SHAPE-MEMORY ALLOY HEART VALVE CLAMPING DEVICE

形状记忆合金心瓣膜夹紧装置

• 批准号: 3501813
• 负责人: A DAVID JOHNSON
• 金额: $ 4.89万
• 依托单位: TINI ALLOY COMPANY
• 依托单位国家: 美国
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-07-01 至 1990-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3501813
• 关键词: alloys; biomaterial development /preparation; heart valves; nickel; prosthetic heart valve; titanium

The overwhelming majority of mechanical heart valves are constructed using parts coated with pyrolytic carbon because of its incredible wear characteristics, biocompatibility, and non-thrombogenicity. Unfortunately, current designs require that their pyrolytic carbon components be deformed (stressed) and handled excessively in order to complete valve assembly. These manipulations may cause defects which can result in thrombosis or premature mechanical failure of the valve. Newer designs are attempting to circumvent this problem by adding a stiffening ring to the valves. The addition of a stiffening ring simplifies the assembly process and minimizes handling. The advantages inherent in using stiffening ring can be optimized if the attachment mechanism is properly designed. TiNi Alloy Company herein proposes to develop an innovative mechanism for the attachment of a stiffening ring to a mechanical heart valve prothesis using an intermediate locking ring made from nickel-titanium shape-memory alloy. The purpose of the novel design is to permit a slip-fit assembly of a stiffening ring around a heart valve housing. the locking ring's shape- memory properties will secure the stiffening ring to the valve housing while minimizing valve handling and stress. This development will improve heart valve quality and reliability.

绝大多数的机械心脏瓣膜都是用 由于其令人难以置信的耐磨性， 特性、生物相容性和非血栓形成性。 不幸的是， 目前的设计要求它们的热解碳部件变形 （受压）并过度操作，以完成阀门组装。 这些操作可能会导致缺陷，从而导致血栓形成， 瓣膜过早机械失效。 新的设计试图 通过在阀上增加加强环来避免这个问题。 的 加强环的增加简化了组装过程 装卸. 使用加强环的固有优点可以是 如果适当地设计附接机构，则可以优化。 TiNi合金公司在此建议开发一种创新机制， 加强环与机械心脏瓣膜假体的连接 使用由镍钛形状记忆材料制成的中间锁定环 合金 新颖设计的目的是允许滑动配合组件， 围绕心脏瓣膜外壳的加强环。 锁环的形状 记忆特性将加强环固定到阀壳体上 同时使阀操作和应力最小化。 这一发展将改善 心脏瓣膜质量和可靠性。