Engineering Microbial Consortia for Industry
工业工程微生物联盟
基本信息
- 批准号:EP/S020705/1
- 负责人:
- 金额:$ 2.35万
- 依托单位:
- 依托单位国家:英国
- 项目类别:Research Grant
- 财政年份:2019
- 资助国家:英国
- 起止时间:2019 至 无数据
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Microbial communities inhabit our entire planet and play a vital role in biogeochemical processes through to human health. Although we have exploited these consortia for a variety of biotechnology processes, rapid technological advances have led to the emerging field of 'microbiome engineering', ripe for exploitation across a plethora of industries, and play a major role in facing grand challenges in health, food, energy and environment. This travel grant is focussed on translating knowledge of natural microbial diversity data, and combining this with expertise in microfluidic screening platforms, quantitative omics technologies and mathematical models to describe mixed-culture interactions for generating synthetic microbial consortia for industry.Our previous work has revealed fundamental mechanisms by which microbes work together and we have translated this for industry at pilot scale. However, we have also encountered many unknowns to advance the field into more complex systems, particularly where we can recover multiple resources from waste, rather than just detoxify it. To enable us to move into more design led approaches for constructing microbial communities, I have identified global leaders in their field, and the goal is to exchange knowledge and data and generate new exciting and ambitious grant proposals in engineering microbial consortia for industry.
微生物群落居住在我们的整个星球上,并在生物地球化学过程中发挥着至关重要的作用。虽然我们已经利用这些财团进行各种生物技术过程,但快速的技术进步已经导致了“微生物组工程”的新兴领域,成熟用于众多行业的开发,并在面临健康,食品,能源和环境的重大挑战中发挥重要作用。这项旅行资助的重点是翻译自然微生物多样性数据的知识,并将其与微流体筛选平台,定量组学技术和数学模型的专业知识相结合,以描述混合培养物的相互作用,为工业生产合成微生物财团。我们以前的工作揭示了微生物协同工作的基本机制,我们已经在中试规模上将其翻译为工业。然而,我们也遇到了许多未知因素,将该领域推进到更复杂的系统中,特别是我们可以从废物中回收多种资源,而不仅仅是解毒。为了使我们能够进入更多以设计为主导的方法来构建微生物群落,我已经确定了该领域的全球领导者,其目标是交换知识和数据,并在工业微生物工程联合体方面产生新的令人兴奋和雄心勃勃的资助提案。
项目成果
期刊论文数量(5)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Effective pretreatment of lignocellulosic co-substrates using barley straw-adapted microbial consortia to enhanced biomethanation by anaerobic digestion.
- DOI:10.1016/j.biortech.2020.124437
- 发表时间:2020-11
- 期刊:
- 影响因子:11.4
- 作者:M. Raut;J. Pandhal;P. Wright
- 通讯作者:M. Raut;J. Pandhal;P. Wright
Adapting the algal microbiome for growth on domestic landfill leachate.
- DOI:10.1016/j.biortech.2020.124246
- 发表时间:2021-01
- 期刊:
- 影响因子:11.4
- 作者:K. Okurowska;E. Karunakaran;A. AL-fartoosy;Narciso Couto;J. Pandhal
- 通讯作者:K. Okurowska;E. Karunakaran;A. AL-fartoosy;Narciso Couto;J. Pandhal
Pathways to economic viability: a pilot scale and techno-economic assessment for algal bioremediation of challenging waste streams
经济可行性之路:具有挑战性的废物流的藻类生物修复的试点规模和技术经济评估
- DOI:10.1039/d0ew00700e
- 发表时间:2020
- 期刊:
- 影响因子:0
- 作者:Leflay H
- 通讯作者:Leflay H
Novel cis-regulatory elements as synthetic promoters to drive recombinant protein expression from the Chlamydomonas reinhardtii nuclear genome.
新型顺式调控元件作为合成启动子,驱动莱茵衣藻核基因组的重组蛋白表达。
- DOI:10.1016/j.nbt.2022.01.001
- 发表时间:2022
- 期刊:
- 影响因子:5.4
- 作者:McQuillan JL
- 通讯作者:McQuillan JL
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Jagroop Pandhal其他文献
N-Linked glycoengineering for human therapeutic proteins in bacteria
- DOI:
10.1007/s10529-010-0289-6 - 发表时间:
2010-05-07 - 期刊:
- 影响因子:2.100
- 作者:
Jagroop Pandhal;Phillip C. Wright - 通讯作者:
Phillip C. Wright
Synthetic microbial ecosystems for biotechnology
- DOI:
10.1007/s10529-014-1480-y - 发表时间:
2014-02-22 - 期刊:
- 影响因子:2.100
- 作者:
Jagroop Pandhal;Josselin Noirel - 通讯作者:
Josselin Noirel
Emission control and carbon capture from diesel generators and engines: A decade-long perspective
柴油发电机和发动机的排放控制及碳捕集:十年的视角
- DOI:
10.1016/j.ccst.2025.100379 - 发表时间:
2025-03-01 - 期刊:
- 影响因子:10.500
- 作者:
Shervan Babamohammadi;Amy R Birss;Hamid Pouran;Jagroop Pandhal;Tohid N. Borhani - 通讯作者:
Tohid N. Borhani
Large-scale cultivation of emSynechocystis/em sp. PCC6803 for the production of Poly(3-hydroxybutyrate) and its potential applications in the manufacturing of bulk and medical prototypes
emsynechocystis/em sp的大规模培养。 PCC6803用于生产聚(3-羟基丁酸)及其在批量和医疗原型制造中的潜在应用
- DOI:
10.1016/j.nbt.2024.08.497 - 发表时间:
2024-11-25 - 期刊:
- 影响因子:4.900
- 作者:
Elbaraa Elghazy;Syed Mohammad Daniel Syed Mohamed;Kamonchanok Wianglor;Santosh Tetali;Mahendra Raut;Ipsita Roy;Jagroop Pandhal - 通讯作者:
Jagroop Pandhal
Isolation and characterisation of microsatellite loci in the papillose woolly bat, Kerivoula papillosa (Chiroptera: Vespertilionidae)
- DOI:
10.1007/s10592-007-9384-1 - 发表时间:
2007-08-02 - 期刊:
- 影响因子:1.700
- 作者:
Matthew J. Struebig;Gavin J. Horsburgh;Jagroop Pandhal;Alison Triggs;Akbar Zubaid;Tigga Kingston;Deborah A. Dawson;Stephen J. Rossiter - 通讯作者:
Stephen J. Rossiter
Jagroop Pandhal的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Jagroop Pandhal', 18)}}的其他基金
Sustainable manufacture of biodegradable film packaging from recalcitrant waste streams
利用顽固废物流可持续制造可生物降解薄膜包装
- 批准号:
EP/X021440/1 - 财政年份:2023
- 资助金额:
$ 2.35万 - 项目类别:
Research Grant
World's first biologically-activated aerosols: for carbon capture without the need for storage
世界上第一个生物活性气溶胶:无需储存即可捕获碳
- 批准号:
EP/X016951/1 - 财政年份:2022
- 资助金额:
$ 2.35万 - 项目类别:
Research Grant
Detoxification and Multi-Resource Recovery from Landfill Leachate
垃圾渗滤液的无毒化和多资源回收
- 批准号:
NE/P016820/1 - 财政年份:2017
- 资助金额:
$ 2.35万 - 项目类别:
Research Grant
The potential to restore eutrophic freshwater systems in the UK with economic benefits
恢复英国富营养化淡水系统并带来经济效益的潜力
- 批准号:
NE/K015591/1 - 财政年份:2013
- 资助金额:
$ 2.35万 - 项目类别:
Research Grant
Impact of Algal Harvesting Technology on Ecosystem Function
藻类捕捞技术对生态系统功能的影响
- 批准号:
NE/J024767/1 - 财政年份:2012
- 资助金额:
$ 2.35万 - 项目类别:
Fellowship
相似国自然基金
水热炭的微生物陈化(Microbial-aged Hydrochar)及其对稻田氨挥发的影响机制
- 批准号:41877090
- 批准年份:2018
- 资助金额:61.0 万元
- 项目类别:面上项目
相似海外基金
CAREER: Selective activation of catalytic RNA to control energy flow in microbial consortia
职业:选择性激活催化 RNA 以控制微生物群落中的能量流
- 批准号:
2237512 - 财政年份:2023
- 资助金额:
$ 2.35万 - 项目类别:
Continuing Grant
Collaborative Research: Synthetic microbial consortia for organismal resilience and reproducible ecosystem services in changing environments
合作研究:在不断变化的环境中实现有机体恢复力和可再生生态系统服务的合成微生物群落
- 批准号:
2300058 - 财政年份:2023
- 资助金额:
$ 2.35万 - 项目类别:
Standard Grant
Collaborative Research: Synthetic microbial consortia for organismal resilience and reproducible ecosystem services in changing environments
合作研究:在不断变化的环境中实现有机体恢复力和可再生生态系统服务的合成微生物群落
- 批准号:
2300059 - 财政年份:2023
- 资助金额:
$ 2.35万 - 项目类别:
Standard Grant
Collaborative Research: Synthetic microbial consortia for organismal resilience and reproducible ecosystem services in changing environments
合作研究:在不断变化的环境中实现有机体恢复力和可再生生态系统服务的合成微生物群落
- 批准号:
2300057 - 财政年份:2023
- 资助金额:
$ 2.35万 - 项目类别:
Standard Grant
Discovery of New microbial consortia for the degradation and biovalorisation of Polypropylene
发现用于聚丙烯降解和生物价值的新微生物群落
- 批准号:
2898891 - 财政年份:2023
- 资助金额:
$ 2.35万 - 项目类别:
Studentship
RUI: Synergistic biodegradation of polyethylene terepthalate (PET) plastic by microbial consortia
RUI:微生物群落对聚对苯二甲酸乙二醇酯 (PET) 塑料的协同生物降解
- 批准号:
2246498 - 财政年份:2023
- 资助金额:
$ 2.35万 - 项目类别:
Standard Grant
URoL:EN: A non-parametric framework to understand emergent behaviors of microbial consortia
URoL:EN:理解微生物群落紧急行为的非参数框架
- 批准号:
2222403 - 财政年份:2022
- 资助金额:
$ 2.35万 - 项目类别:
Standard Grant
Discovery of bacterial consortia to treat recurrent vulvovaginal candidiasis: a generalizable platform for phenotypic microbial community screening
发现治疗复发性外阴阴道念珠菌病的细菌群落:表型微生物群落筛查的通用平台
- 批准号:
10383360 - 财政年份:2022
- 资助金额:
$ 2.35万 - 项目类别:
Understanding variability in microbial biomining and bioremediation consortia; adaptation mechanisms for multiple extremes.
了解微生物生物采矿和生物修复联盟的变异性;
- 批准号:
RGPIN-2019-06985 - 财政年份:2022
- 资助金额:
$ 2.35万 - 项目类别:
Discovery Grants Program - Individual
FMRG: Bio: CAS: Distributed methane conversion into value chemicals via synthetic microbial consortia
FMRG:生物:CAS:通过合成微生物群将分布式甲烷转化为有价值的化学品
- 批准号:
2229070 - 财政年份:2022
- 资助金额:
$ 2.35万 - 项目类别:
Standard Grant