ISOMETRIC EXERCISE AND AGE--CARDIOVASCULAR-SYMPATHOADRENAL-METABOLIC RESPONSES

等长运动和年龄——心血管交感肾上腺代谢反应

• 批准号: 3823176
• 负责人: A ZIEMBA
• 金额: --
• 依托单位: NATIONAL INSTITUTE ON AGING
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3823176
• 关键词: aging; blood pressure; body weight; catecholamines; exercise; gender difference; heart rate; human middle age (35-64); human old age (65+); metabolism; muscle contraction; obesity; physical fitness; young adult human (21-34)

Static (isometric) muscle contractions are common components of effort in performing daily activities. The problem of static exercise becomes important since isometric contractions cause marked increases in blood pressure and catecholamine levels. This study is designed to describe the relationships among age, sex, race, body weight, pattern of body fat distribution, level of physical fitness, and static exercise responses. The subjects for the study are selected from four volunteer groups: participants in the Johns Hopkins Academic Teaching Nursing Home, the Baltimore Longitudinal Study of Aging (BLSA), the Senior Athletes Study and volunteers working in this environment. They are divided into four age groups: 20-45, 45-59, 60-74 and 75 and over years. They range in obesity from lean to moderately obese and are further subdivided into subgroups of subjects representing upper and lower body segment type of obesity. The experimental protocol is the same for all subjects: sustained hand-grip exercise on a hand dynamometer at 30% of their individual maximal voluntary force to fatigue (usually 3 - 6 minutes). Before the test, at one minute intervals during the test, and 3 minutes after its termination, blood pressure, heart rate and blood samples for catecholamines, glucose and free fatty acids are taken. To date, a total of 170 subjects have been studied from several population groups. The goal of recruiting 160 subjects has just been surpassed and analyses of the results will be conducted in the coming year.

静态(等长)肌肉收缩是运动中常见的力量成分 进行日常活动。静态锻炼的问题变成了 重要的是因为等长收缩会导致血液显著增加 血压和儿茶酚胺水平。这项研究旨在描述 年龄、性别、种族、体重、体脂类型的关系 分布、体能水平和静态运动反应。 研究对象是从四个志愿者小组中挑选出来的： 约翰霍普金斯大学教学疗养院的学员 巴尔的摩老龄化纵向研究(BLSA)，高级运动员研究和 在这种环境中工作的志愿者。他们分为四个年龄段 年龄：20-45岁、45-59岁、60-74岁和75岁及以上。他们的肥胖程度各不相同 从瘦到中度肥胖，并进一步细分为 代表上下身节段型肥胖的受试者。这个 所有受试者的实验方案都是相同的：持续握手 在手摇测功机上以30%的个人最大自愿性进行锻炼 用力至疲劳(通常为3-6分钟)。在测试之前，在一分钟 在试验期间和终止后3分钟的间隔内，取血 血压、心率和血样中儿茶酚胺、葡萄糖和游离 脂肪酸被摄取了。到目前为止，共有170名受试者被研究。 来自几个人口群体。招募160名受试者的目标是 刚刚被超越，对结果的分析将在 即将到来的一年。