AUDITORY BRAINSTEM RESPONSE (ABR) ANALYSIS AND INTERPRETATION EXPERT SYSTEM

这个项目的目标是建立一个专家系统来 分析和解释听觉脑干反应(ABR)，以及 脑干对声刺激的电生理反应。专家 ABR的读数在临床决策中是必不可少的 耳蜗后症。 我们开发了一个基于规则的专家系统，用于执行神经诊断 对听觉脑干反应的解释。这个系统是 在IBM PC上开发的商业专家系统外壳专家系统和 现已在美国国立卫生研究院听力学诊所投入使用。一场题为“安”的演讲 听觉脑干反应解释的专家系统方法“， 描述了我们的专家系统是在1988年的美国 在波士顿召开的听力学会会议。 开发和使用该系统的经验表明， 产生更准确的ABR神经诊断解释的可能性 使用机器学习方法直接从ABR数据中提取范例。 相应地，研究了直接获取诊断专家系统规则的方法 来自ABR的数据已启动。一次演讲的摘要，题目是， 听性脑干反应的受试者工作特性分析 《潜伏期》，已提交给1989年的美国 在新奥尔良召开的听觉学会会议。这场演讲涵盖了我们早期的 具有针对关键业务的高精度数据派生规则经验 耳蜗术后与耳蜗病的鉴别。

The objective of this project has been to build an expert system to analyze and interpret the Auditory Brainstem Response (ABR), an electrophysiological response of the brainstem to acoustic stimuli. Expert reading of the ABR is essential in clinical decisions concerning retrocochlear disorders. We developed a rule-based expert system that performs neurodiagnostic interpretation of the auditory brainstem response. The system was developed on the IBM PC with the commercial expert system shell GURU and is now operational in the NIH audiology clinic. A talk entitled, "An Expert System Approach to Auditory Brainstem Response Interpretation", which describes our expert system was given at the 1988 American Audiologic Society Meeting in Boston. Experience in developing and using the system has suggested the possibility of generating more accurate ABR neurodiagnostic interpretation paradigms directly from ABR data using machine-learning methods. Accordingly, a study to derive diagnostic expert system rules directly from ABR data has been initiated. An abstract for a talk entitled, "Receiver Operating Characteristic Analysis of Auditory Brainstem Response Latency", has been submitted for presentation at the 1989 American Auditory Society Meeting in New Orleans. This talk covers our early experience with high-accuracy, data-derived rules for the critical differentiation of retrocochlear and cochlear disorders.