Control of corticalisation by SOCS3 in osteocytes
Control of corticalisation by SOCS3 in osteocytes
批准号:
nhmrc : 1120978
负责人:
A/Pr Natalie Sims
金额:
$61.46万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2017
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2017-01-01 至 2020-12-31
中文摘要
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英文摘要
Treating and preventing painful fractures could be improved by strengthening cortical bone – the hard outer shell of all bones in the skeleton. We don’t know how cortical bone forms, but if we did, we could improve its strength. We have found that a brain-like network of cells inside the skeleton, called osteocytes, use a specific signal, called SOCS3, to make strong cortical bone. This study will find out how SOCS3 works and find new ways to make cortical bone strong and healthy.
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会议论文
Discovering novel pathways that strengthen bone
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批准号:nhmrc : GNT1154819
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项目类别:Research Fellowships
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资助金额:$64.92万
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财政年份:2019
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负责人:A/Pr Natalie Sims
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依托单位:
Control of corticalisation by SOCS3 in osteocytes
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批准号:nhmrc : GNT1120978
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项目类别:Project Grants
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资助金额:$89.96万
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财政年份:2017
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负责人:A/Pr Natalie Sims
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依托单位:
IL-6 classic and trans-signalling in bone physiology and pathology
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批准号:nhmrc : GNT1081242
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项目类别:Project Grants
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资助金额:$70.42万
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财政年份:2015
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负责人:A/Pr Natalie Sims
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依托单位:
IL-6 classic and trans-signalling in bone physiology and pathology
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批准号:nhmrc : 1081242
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项目类别:Project Grants
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资助金额:$48.77万
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财政年份:2015
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负责人:A/Pr Natalie Sims
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依托单位:
Osteocytic SOCS3 controls STAT3:STAT1 balance and bone formation
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批准号:nhmrc : 1058625
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项目类别:Project Grants
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资助金额:$43.22万
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财政年份:2014
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负责人:A/Pr Natalie Sims
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依托单位:
Regulation of bone formation and resorption by osteoblastic EphrinB2/EphB4 signalling
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批准号:nhmrc : 1042129
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项目类别:Project Grants
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资助金额:$43.24万
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财政年份:2013
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负责人:A/Pr Natalie Sims
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依托单位:
Research Fellowship
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批准号:nhmrc : 1019703
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项目类别:Research Fellowships
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资助金额:$49.32万
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财政年份:2012
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负责人:A/Pr Natalie Sims
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依托单位:
Influence of osteocytes on anabolic bone therapies
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批准号:nhmrc : 1002730
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项目类别:NHMRC Project Grants
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资助金额:$39.14万
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财政年份:2011
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负责人:A/Pr Natalie Sims
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依托单位:
Structural and functional analysis of oncostatin M receptor signalling complexes
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批准号:nhmrc : 1004945
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项目类别:Project Grants
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资助金额:$34.63万
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财政年份:2011
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负责人:A/Pr Natalie Sims
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依托单位:
gp130 signalling in bone formation and resorption
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批准号:nhmrc : 1002728
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项目类别:NHMRC Project Grants
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资助金额:$43.53万
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财政年份:2011
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负责人:A/Pr Natalie Sims
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依托单位:
ROLE OF EPHRIN-EPH SIGNALLING IN THE FORMATION PHASE OF BONE REMODELLING
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批准号:nhmrc : 620200
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项目类别:NHMRC Project Grants
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资助金额:$35.9万
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财政年份:2010
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负责人:A/Pr Natalie Sims
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依托单位:
Research Fellowship - Grant ID:395513
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批准号:nhmrc : 395513
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项目类别:NHMRC Research Fellowships
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资助金额:$44.35万
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财政年份:2006
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负责人:A/Pr Natalie Sims
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依托单位:
Novel mechanisms for control of osteoclastogenesis in bone and joint disease
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批准号:nhmrc : 247930
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项目类别:Career Development Fellowships
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资助金额:$21.52万
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财政年份:2003
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负责人:A/Pr Natalie Sims
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依托单位:
海外基金