Discovering novel pathways that strengthen bone

发现强化骨骼的新途径

• 批准号: nhmrc : GNT1154819
• 负责人: A/Pr Natalie Sims
• 金额: $ 64.92万
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/discovering-novel-pathways-strengthen-bone/1349157
• 关键词: Discovering; novel; pathways; strengthen; bone

Treatments for skeletal disorders (e.g. osteoporosis, bone destruction by cancer) are limited, partly because of our incomplete understanding of what makes bones strong. I study how bone strength, including both its shape and substance, is controlled by cells in the skeleton, and how this differs between men and women. Answering these fundamental questions about how strong skeletons are made will improve the way we diagnose and treat bone diseases.

骨骼疾病（例如骨质疏松症、癌症引起的骨质破坏）的治疗方法有限，部分原因是我们对骨骼强健的原因不完全了解。我研究骨骼强度（包括其形状和物质）如何由骨骼中的细胞控制，以及男性和女性之间的差异。回答这些关于骨骼如何坚固的基本问题将改善我们诊断和治疗骨骼疾病的方式。