Influence of osteocytes on anabolic bone therapies

骨细胞对骨合成代谢治疗的影响

• 批准号: nhmrc : 1002730
• 负责人: A/Pr Natalie Sims
• 金额: $ 39.14万
• 依托单位: St. Vincent's Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/influence-osteocytes-anabolic-bone-therapies/108854
• 关键词: Influence; osteocytes; anabolic; bone; therapies

This project seeks to define the influence of changes in gene expression in cells called osteocytes, that exist within the substance of bone. These cells form a communication network within the bones of the skeleton, and appear to influence bone formation; changes in gene expression by these cells could influence the efficacy of current and emerging osteoporosis therapies.

该项目旨在确定存在于骨物质中的称为骨细胞的细胞中基因表达变化的影响。这些细胞在骨骼的骨骼内形成通讯网络，并似乎影响骨形成;这些细胞基因表达的变化可能会影响当前和新兴骨质疏松症治疗的疗效。