Control of musculoskeletal function and body composition by androgens in men

男性雄激素对肌肉骨骼功能和身体成分的控制

• 批准号: nhmrc : 1006407
• 负责人: Prof Jeffrey Zajac
• 金额: $ 39.62万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/control-musculoskeletal-function-androgens-men/109172
• 关键词: Control; musculoskeletal; function; body; composition

Male sex hormone or androgen deficiency (AD) is a common, but under-diagnosed condition. AD decreases general well being and contributes to muscle weakness, bone fragility and weight gain. By using cutting edge imaging and molecular technologies, we will help to explain the underlying mechanisms of how AD leads to these negative effects. This should ultimately lead to reduction of adverse outcomes of AD, which include fractures and cardiovascular events.

男性性激素或雄激素缺乏症（AD）是一种常见但诊断不足的疾病。AD降低总体健康状况，并导致肌肉无力、骨脆弱和体重增加。通过使用尖端的成像和分子技术，我们将有助于解释AD如何导致这些负面影响的潜在机制。这将最终导致AD的不良结局减少，包括骨折和心血管事件。