The mechanistic control of bone quality and joint crosstalk by osteocytes
The mechanistic control of bone quality and joint crosstalk by osteocytes
批准号:
10605074
负责人:
Tamara N Alliston
金额:
$9.17万
依托单位国家:
美国
项目类别:
财政年份:
2022
资助国家:
美国
项目状态:
已结题
起止时间:
2022-06-01 至 2023-05-31
关键词:
AblationAcidsAddressAgeAgingAgonistBone DensityBone MatrixBone necrosisCellsClinicalCommunicationCoupledDataDefectDegenerative polyarthritisDevelopmentDiseaseFaceFractureGenesGenetic EpistasisGoalsGrantHealthHistologicHomeostasisHumanHuman GenomeImpairmentIn VitroJointsKnee jointLinkLongevityMetabolismMitochondriaMolecularMusMusculoskeletalOrthologous GeneOsteocytesOutcomeParentsPathway AnalysisPatternPeptide HydrolasesPhenotypePilot ProjectsPlayPopulationProcessPropertyPublishingRegulationRoleSignal TransductionSpecimenTemporomandibular JointTestingWorkage relatedagedaging populationarthropathiesbiobankbonebone fragilitybone lossbone massbone qualitycellular targetingclinical developmentcohortcortical bonedifferential expressiongenome-widehuman dataimprovedin vivojoint destructionloss of functionmitochondrial dysfunctionmouse modelnovelpreventradiological imagingresponseskeletalsuccesstranscriptome sequencing
中文摘要
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英文摘要
PROJECT SUMMARY
Not applicable - no change from parent R01 grant.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Osteocyte-dependent mechanisms of bone cartilage crosstalk in osteoarthritis
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批准号:10727267
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项目类别:
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资助金额:$40.87万
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财政年份:2023
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负责人:Tamara N Alliston
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依托单位:
UCSF Musculoskeletal Training Program
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批准号:10625232
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项目类别:
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资助金额:$24.26万
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财政年份:2023
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负责人:Tamara N Alliston
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依托单位:
Core Center for Musculoskeletal Biology and Medicine (Overall Application)
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批准号:10642787
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项目类别:
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资助金额:$77.42万
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财政年份:2019
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负责人:Tamara N Alliston
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依托单位:
Skeletal Biology and Biomechanics (SBB) Core
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批准号:10215391
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项目类别:
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资助金额:$14.54万
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财政年份:2019
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负责人:Tamara N Alliston
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依托单位:
Core Center for Musculoskeletal Biology and Medicine (Overall Application)
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批准号:10707598
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项目类别:
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资助金额:$17.08万
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财政年份:2019
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负责人:Tamara N Alliston
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依托单位:
Skeletal Biology and Biomechanics (SBB) Core
-
批准号:10642797
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项目类别:
-
资助金额:$14.54万
-
财政年份:2019
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负责人:Tamara N Alliston
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依托单位:
Core Center for Musculoskeletal Biology and Medicine (Overall Application)
-
批准号:10460468
-
项目类别:
-
资助金额:$77.42万
-
财政年份:2019
-
负责人:Tamara N Alliston
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依托单位:
Skeletal Biology and Biomechanics (SBB) Core
-
批准号:10460472
-
项目类别:
-
资助金额:$14.54万
-
财政年份:2019
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负责人:Tamara N Alliston
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依托单位:
Core Center for Musculoskeletal Biology and Medicine (Overall Application)
-
批准号:10215386
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项目类别:
-
资助金额:$77.42万
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财政年份:2019
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负责人:Tamara N Alliston
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依托单位:
AAOS/ORS Tackling Joint Disease by Understanding Crosstalk between Cartilage and Bone Research Symposium
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批准号:9053709
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项目类别:
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资助金额:$1.5万
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财政年份:2015
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负责人:Tamara N Alliston
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依托单位:
The mechanobiology of TGF-beta signaling in chondrocytes
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批准号:8928971
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项目类别:
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资助金额:$22.11万
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财政年份:2014
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负责人:Tamara N Alliston
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依托单位:
The mechanobiology of TGF-beta signaling in chondrocytes
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批准号:8809944
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项目类别:
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资助金额:$18.57万
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财政年份:2014
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负责人:Tamara N Alliston
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依托单位:
The Mechanistic Control of Bone Matrix Material Properties by TGF-beta and Runx2
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批准号:7790648
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项目类别:
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资助金额:$38.23万
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财政年份:2009
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负责人:Tamara N Alliston
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依托单位:
The Mechanistic Control of Bone Matrix Material Properties by TGF-beta and Runx2
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批准号:7653312
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项目类别:
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资助金额:$38.6万
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财政年份:2009
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负责人:Tamara N Alliston
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依托单位:
The mechanistic control of bone quality and joint crosstalk by osteocytes
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批准号:10413198
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项目类别:
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资助金额:$59.13万
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财政年份:2009
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负责人:Tamara N Alliston
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依托单位:
The Mechanistic Control of Bone Matrix Material Properties by TGF-beta and Runx2
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批准号:8024473
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项目类别:
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资助金额:$37.08万
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财政年份:2009
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负责人:Tamara N Alliston
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依托单位:
The mechanistic control of bone extracellular matrix material properties by TGFb
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批准号:9119517
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项目类别:
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资助金额:$39.57万
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财政年份:2009
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负责人:Tamara N Alliston
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依托单位:
The mechanistic control of bone extracellular matrix material properties by TGFb
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批准号:9322754
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项目类别:
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资助金额:$10.0万
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财政年份:2009
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负责人:Tamara N Alliston
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依托单位:
The mechanistic control of bone quality and joint crosstalk by osteocytes
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批准号:10183220
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项目类别:
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资助金额:$57.75万
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财政年份:2009
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负责人:Tamara N Alliston
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依托单位:
The Mechanistic Control of Bone Matrix Material Properties by TGF-beta and Runx2
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批准号:8402547
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项目类别:
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资助金额:$36.33万
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财政年份:2009
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负责人:Tamara N Alliston
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依托单位:
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