EFFECT OF CAFFEINATED BEVERAGES ON COLONIC EPITHELIAL CELLS

含咖啡因饮料对结肠上皮细胞的影响

• 批准号: 3741607
• 负责人: STEVEN J SHIFF
• 金额: --
• 依托单位: ROCKEFELLER UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3741607
• 关键词: beverages; caffeine; colon; dietary constituent; gastrointestinal epithelium; gene mutation; human subject; nutrition related tag; oncogenes

As caffeine can affect cell proliferation in vitro, this research examines the effect of dietary caffeine on the colonic epithelium. Subjects are given a well-controlled diet, with caffeine administered as an independent variable. Assessment of colonic epithelium, caffeine, and Ki-ras oncogene mutations are carried out before, during and after the caffeine introduction.

由于咖啡因可以影响体外细胞增殖， 研究饮食中咖啡因对结肠上皮的影响。 受试者被给予控制良好的饮食，咖啡因作为 独立变量。 结肠上皮、咖啡因和 Ki-ras癌基因突变在肿瘤发生之前、期间和之后进行。 咖啡因介绍