AGE CHANGES IN VISUAL FUNCTION

视觉功能的年龄变化

• 批准号: 3745526
• 负责人: J L FOZARD
• 金额: --
• 依托单位: NATIONAL INSTITUTE ON AGING
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3745526
• 关键词: aging; blood pressure; brightness discrimination; eye disorder diagnosis; female; gender difference; health surveys; human subject; intraocular pressure; longitudinal human study; racial /ethnic difference; vision tests; visual depth perception; visual fields; visual perception; visual photosensitivity

Deterioration of vision is a common problem in the elderly and in recent studies has been demonstrated to be an independent and important contributor to physical disability and frailty. Age associated loss of vision can result from aging and from age-associated pathology. The natural history of vision loss has not been well studied in relationship to the development of eye and other pathology and the differentiation between normal visual aging and pathological changes in vision. Furthermore, little attention has been given to what factors may prevent aging changes in vision and what environmental factors can be altered as the changes begin to occur and as they progress. Research in the BLSA has been designed to address aspects of these age associated changes. (1) Natural history studies have been done for many years, and several longitudinal studies have been reported. Visual acuity and binocular depth perception is measured on first time participants, and longitudinally on women participants in the BLSA. A laboratory based assessment of visual contrast sensitivity continues to be administered, increasing the number of persons with at least two measures to over a hundred. (2) A new study of the relationship between intraocular pressure and systemic blood pressure has been developed and has begun in July 1994. The study will identify possible racial and sex differences in blood pressure/intraocular pressure relationships and the effect of the relationship on vision as measured by changes in the visual field.

视力下降是一个常见的问题， 老年人和最近的研究已被证明是 一个独立的和重要的贡献者， 残疾和脆弱。年龄相关的视力丧失可能 由衰老和与年龄相关的病理学引起。的 视力丧失的自然史尚未得到充分研究 与眼睛和其他器官的发育有关 病理学和正常视力之间的鉴别 衰老和视力的病理变化。此外，委员会认为， 很少有人注意到哪些因素可能 防止视力老化的变化和什么环境 当变化开始发生时， 随着他们的进步。 BLSA的研究旨在解决 这些与年龄相关的变化。 (1)自然历史研究已经完成了许多 多年来，一些纵向研究已经 报道视力和双眼深度知觉是 对首次参与者进行测量， 在BLSA的女性参与者。基于实验室 视觉对比敏感度的评估仍然是 管理，增加人数与at 从两小节到一百多小节 (2)一项新的研究， 眼内压和全身血压已经被 已于1994年7月开始开发。这项研究将 确定血液中可能存在的种族和性别差异 压力/眼内压关系和 关系对视力的影响， 视野的变化。