AGE CHANGES IN VISUAL FUNCTION

视觉功能的年龄变化

• 批准号: 2565736
• 负责人: J L FOZARD
• 金额: --
• 依托单位: NATIONAL INSTITUTE ON AGING
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/2565736
• 关键词: aging; blood pressure; brightness discrimination; clinical research; epidemiology; gender difference; health surveys; human subject; intraocular pressure; longitudinal human study; pathologic process; racial /ethnic difference; vision tests; visual fields; visual perception; visual photosensitivity

Deterioration of vision is a common problem in the elderly and in recent studies has been demonstrated to be an independent and important contributor to physical disability and frailty. Age associated loss of visi can result from aging and from age-associated pathology. The natural history of vision loss has not been well studied in relationship to the development of eye and other pathology and the differentiation between normal visual aging and pathological changes in vision. Furthermore, little attention has been given to what factors may prevent aging changes in vision and what environmental factors can be altered as the changes begin to occur and as they progress. Research in the BLSA has been designed to address aspects of these age associated changes. (1) Natural history studies have been done for many years, and several longitudinal studies have been reported. A laboratory based assessment of visual contrast sensitivity continues to be administered, increasing the number of persons with at least two measures to over two hundred. (2) A new study of the relationship between intraocular pressure and systemic blood pressure was begun in July 1994. The goal of the study is to identify possible racial and sex differences in blood pressure/intraocular pressure relationships and the effect of the relationship on vision as measured by changes in visual field sensitivity.

视力下降是老年人的常见问题， 研究已被证明是一个独立的和重要的 导致身体残疾和虚弱。与年龄相关的视力丧失 可能是由于衰老和与年龄相关的病理学。自然 视力丧失的历史还没有得到很好的研究， 眼睛和其他病理学的发展以及 正常的视觉老化和视觉的病理变化。而且小 人们已经开始关注哪些因素可能会阻止衰老的变化， 视觉和什么样的环境因素可以改变的变化 开始发生和发展。 BLSA的研究旨在解决这些年龄的问题 相关的变化。 (1)自然历史研究已经进行了很多年， 纵向研究报告。基于实验室的评估 的视觉对比敏感度继续管理，增加 人数至少有两个措施，以超过二百人。 (2)眼内压与眼压关系的新研究 1994年7月开始测量全身血压。该研究的目的 是找出血液中可能存在的种族和性别差异 压力/眼内压的关系以及 通过视野敏感度的变化测量的视觉关系。