NanoRAM: Emerging Nanotools for Soft Matter Characterisation and Manipulation

NanoRAM：用于软物质表征和操纵的新兴纳米工具

• 批准号: EP/Y032047/1
• 负责人: Michelle Peckham
• 金额: $ 33.22万
• 依托单位: University of Leeds
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2024
• 资助国家: 英国
• 起止时间: 2024 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FY032047%2F1
• 关键词: NanoRAM; Emerging; Nanotools; Soft; Matter

Advanced nanotools including atomic force microscopy, optical microscopy and correlative microscopy are enabling techniques for discoveries and knowledge generation in nanoscale science and technology. Many R&D efforts have been directed towards the performance improvement of such kinds of techniques for soft matter. However, the greatest challenge faced by these leading edge techniques is the realization of high spatiotemporal resolution, non-invasive, multi-scale and multi-dimensional imaging and manipulation. We therefore propose NanoRAM, a 10 ESR Marie Sklodowska Curie Action Doctoral Network by close collaboration between academic and industrial partners around the theme of innovative nanotools and their industrial applications. NanoRAM will train a new generation of ESRs in the development and application of newly developed manipulation and characterisation nanotools in soft matter research. ESRs will be cross-pollinated with concepts and skills in instrumentation and soft matter characterisation, in particular in fast nanomechanical spectroscopy, nano-robotics, correlative super-resolution nanoscopy, nano biomechanics and mechanotransduction. These skills are applied to reveal for the first time the fast, high resolution, multi-level and 3D information forsingle cell biomechanics and nanomedicine. Excellent training in new scientific and complementary skills, combined with international and intersectoral work experience, will instil an innovative, creative and entrepreneurial mind-set in ESRs, maximising economic benefits based on scientific discoveries. These specialised, highly trained ESRs will have greatly enhanced career prospects and qualifications for access to responsibility job positions in the private and public sectors. The ultimate goal of NanoRAM is to consolidate Europe as the world leader in innovative nanotool techniques and their emerging applications in soft matter fields such as biomechanics, mechanobiology, and nanomedicines.

先进的纳米工具，包括原子力显微镜、光学显微镜和相关显微镜，使纳米科学和技术中的发现和知识产生成为可能。许多研发工作都是针对软物质这类技术的性能改进而进行的。然而，这些前沿技术面临的最大挑战是实现高时空分辨率、无创、多尺度和多维的成像和操作。因此，我们提出了NanoRAM，一个10 ESR的Marie Sklodowska Curie Action博士网络，由学术和工业合作伙伴围绕创新的纳米工具及其工业应用这一主题密切合作。NanoRAM将培训新一代ESRS在软物质研究中开发和应用新开发的操纵和表征纳米工具。ESRS将与仪器和软物质表征方面的概念和技能交叉授粉，特别是在快速纳米机械光谱学、纳米机器人、相关超分辨率纳米显微镜、纳米生物力学和机械转导方面。这些技术首次被应用于揭示单细胞生物力学和纳米医学的快速、高分辨率、多层次和三维信息。在新的科学技能和互补技能方面的出色培训，结合国际和跨部门的工作经验，将为ESRS注入创新、创造性和企业家精神，根据科学发现实现经济效益最大化。这些专业的、训练有素的ESRS将极大地提高职业前景和获得私营和公共部门责任工作职位的资格。NanoRAM的最终目标是巩固欧洲在创新纳米工具技术及其在生物力学、机械生物学和纳米医学等软物质领域的新兴应用方面的世界领先地位。