INTERVENTION COORDINATING CENTER

干预协调中心

• 批准号: 3551036
• 负责人: ARLENE W CAGGIULA
• 金额: $ 17.68万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-09-30 至 1995-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3551036
• 关键词: biomedical resource; blood lipid; blood pressure; cooperative study; data collection methodology /evaluation; diabetes mellitus; hemodialysis; human therapy evaluation; nutrition; nutrition related tag; technical writing; therapy compliance

The overall objective of this proposal is to design a high quality Intervention Coordinating Center (ICC) which would serve the Reduction in Mortality and Morbidity Among Hemodialysis Patients (RMMAHP) Pilot Study and support the achievement of the five major objectives of that study. These are to: 1) design a pilot study protocol and write a Manual of Operations; 2) determine recruitment potential for a full-scale study; 3) detect short-term adverse effects associated with the experimental interventions; 4) implement procedures for the management of blood pressure, diabetes, and blood lipids and evaluate compliance to these modalities; 5) develop an inclusive intervention counseling model and a 'state of the art' program to insure care of the vascular access site; and 6) produce data which will allow for a better estimate of sample size required for a full-scale study. In order to fulfill these objectives the ICC will work collaboratively with the clinical centers, the Data Coordinating Center, and the staff of the National Institute of Diabetes and Digestive and Kidney Disease.

本提案的总体目标是设计一个高质量的 干预协调中心（ICC）将为减少 血液透析患者死亡率和死亡率（RMMAHP）初探性研究 并支持实现该研究的五大目标。 这些是：1）设计试点研究方案并编写手册 2）确定全面研究的招募潜力; 3） 检测与实验相关的短期不良反应 干预措施; 4）实施血液管理程序 血压、糖尿病和血脂，并评估对这些指标的依从性 （5）发展包容性干预咨询模式， “最先进”计划，以确保血管穿刺部位的护理; 和6）产生数据，以便更好地估计样本量 这是一项全面研究所需的。 为了实现这些目标 ICC将与临床中心、数据中心、 协调中心和国家糖尿病研究所的工作人员 以及消化和肾脏疾病。