Dark, sticky and treacherous: targeting dietary advanced glycation end-products (AGEs) in female infertility

黑暗、粘稠且危险：针对女性不孕症的饮食晚期糖基化终产物 (AGE)

• 批准号: nhmrc : GNT1164771
• 负责人: Dr Nicole Kellow
• 金额: $ 32.72万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/dark-sticky-treacherous-female-infertility/1349379
• 关键词: Dark; sticky; treacherous; targeting; dietary

Advanced Glycation Endproducts (AGEs) are formed when sugars and proteins stick together, resulting in the brown colour, caramel flavour and sticky surface of heated foods. AGEs in food can be absorbed into our bodies and damage body tissues. Obese women who struggle to become pregnant have an increased build-up of AGEs in their uterus, which inhibits their ability to conceive. I will investigate whether a low-AGE diet can improve fertility outcomes in obese women who are unable to get pregnant.

当糖和蛋白质粘在一起时，就会形成高级糖基化终产物 (AGE)，从而导致加热食品呈现棕色、焦糖味和粘性表面。食物中的 AGE 会被我们的身体吸收并损害身体组织。难以怀孕的肥胖女性的子宫内 AGE 积累增加，从而抑制了她们的受孕能力。我将研究低 AGE 饮食是否可以改善无法怀孕的肥胖女性的生育结果。