Dark, sticky and treacherous: targeting dietary advanced glycation end-products (AGEs) in female infertility

黑暗、粘稠且危险：针对女性不孕症的饮食晚期糖基化终产物 (AGE)

• 批准号: nhmrc : GNT1164771
• 负责人: Dr Nicole Kellow
• 金额: $ 32.72万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/dark-sticky-treacherous-female-infertility/1349379
• 关键词: Dark; sticky; treacherous; targeting; dietary

Advanced Glycation Endproducts (AGEs) are formed when sugars and proteins stick together, resulting in the brown colour, caramel flavour and sticky surface of heated foods. AGEs in food can be absorbed into our bodies and damage body tissues. Obese women who struggle to become pregnant have an increased build-up of AGEs in their uterus, which inhibits their ability to conceive. I will investigate whether a low-AGE diet can improve fertility outcomes in obese women who are unable to get pregnant.

糖基化终产物（AGEs）是糖和蛋白质粘在一起时形成的，导致加热食物的棕色，焦糖味和粘性表面。食物中的AGEs会被人体吸收，损害人体组织。努力怀孕的肥胖妇女子宫中AGEs的积累增加，这会抑制她们的怀孕能力。我将调查低AGE饮食是否可以改善无法怀孕的肥胖妇女的生育结果。