IDENTIFICATION OF OXACILLIN RESISTANT STRAINS OF STAPHYLOCOCCUS AUREUS

苯唑西林耐药沙门氏菌的多中心研究。金黄色葡萄球菌已就位， 应在一年内完成。噬菌体类型已经并将继续 用于苯唑西林耐药菌株的指纹图谱。我们 有证据表明，苯唑西林耐药菌株不可逆， 克拉维酸数量很少，苯唑西林抗性S.金黄色 在许多美国医院中，以单一的优势菌株为代表。S. 金黄色葡萄球菌，其中苯唑西林耐药性在以下存在下降低： 克拉维酸，高β内酰胺酶的生产者，有另一个不同的， 噬菌体模式我们也在研究苯唑西林耐药性的丧失率 在从治疗的患者培养菌株之后。这一阶段将 包括直接从临床样品进行的初始敏感性测试， 然后在连续传代培养期间进行测试。这具有重要 对这些S.金黄色葡萄球菌菌株，因为它们开始 在最初的培养物上立即失去抵抗力。

A multi-center study of oxacillin resistant S. aureus is in place and should be completed within a year. Phage types have been, and will continue to be used to fingerprint strains of the oxacillin resistant species. We have evidence that strains with oxacillin resistance not reversible by clavulanic acid are few in number, and that oxacillin resistant S. aureus is represented in many U.S. hospitals by a single predominant strain. S. aureus in which oxacillin resistance is reduced in the presence of clavulanic acid, the hyperbetalactamase producers, have another, distinct phage pattern. We also are studying loss rates of oxacillin resistance after the strains are cultured from the treated patient. This phase will include initial sensitivity tests done directly from clinical samples, followed by tests done during serial subcultures. This has important bearing on sensitivity testing of these S. aureus strains, since they begin to lose resistance immediately, on initial cultures.