PREDICTIVE VALUE OF SALIVARY ASSAYS IN PREDICTING DENTAL CARIES

唾液检测在预测龋齿中的预测价值

• 批准号: 3839251
• 负责人: A KINGMAN
• 金额: --
• 依托单位: NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3839251
• 关键词: Scandinavian; Scandinavian country; adolescence (12-20); biomarker; dental caries; disease /disorder proneness /risk; microorganism culture; oral bacteria; saliva

Identifying subjects who are likely to develop high levels of dental caries based on results from simple salivary assays for microorganism counts was the focal point of this study. It is know that these microorganism assays are of limited value in areas with low caries prevalence. Therefore, we studied an adolescent Icelandic population whose mean DMFS scores were roughly 3 times that of their US counterparts. The basic findings were that the microorganism assays were also of limited value in a high caries prevalence population, although their positive predictive values were slightly higher than those typically reported in a low caries prevalence population. They also proved not to be significantly better than using the initial DMFS scores for individual subjects, suggesting that they were of no cost-benefit value in targeting subjects at high risk for caries.

识别可能发展高水平牙科疾病的受试者 根据唾液微生物简单测定结果的龋齿 计数是这项研究的重点。 据了解，这些 微生物检测在低龋地区的价值有限 普遍性。 因此，我们研究了一个青少年冰岛人口 他们的平均DMFS分数大约是美国的3倍， 同行 基本的发现是，微生物测定也是 在高龋齿患病率人群中的价值有限，尽管他们 阳性预测值略高于那些典型的 在低龋齿患病率人群中报告。 他们也证明了 明显优于使用初始DMFS分数 个体受试者，表明它们没有成本效益价值 针对龋齿高危人群。