METHODS FOR ANALYZING LONGITUDINAL PERIODONTAL DATA

纵向牙周数据分析方法

• 批准号: 3963763
• 负责人: A KINGMAN
• 金额: --
• 依托单位: NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3963763
• 关键词: epidemiology; human subject; human therapy evaluation; longitudinal human study; periodontium disorder; statistics /biometry

Statistical methods are presented for analyzing longitudinal periodontal loss of attachment data using subject based summary measures. The methods are illustrated by using data from a 2-year clinical study in which a conservative periodontal therapy was evaluated. The 2-year study period was divided into the lst 6-month period (treatment period) and the 2nd 18 months (maintenance period). Individual sites within patients were classified by their initial probing pocket depth values: shallow, moderate or deep. Treatment and maintenance effects were assessed by using multivariate statistical methods (Hotelling T-square tests) jointly, and for each class of sites, separately. For this data set it was shown that this conservative therapy produced significant improvement for deep sites, minor improvement for moderate sites, and significant deterioration for shallow sites.

统计方法，提出了分析纵向牙周 使用基于受试者的汇总测量丢失附件数据。 的方法 通过使用来自2年临床研究的数据来说明， 评价牙周保守治疗。 2年研究期 分为治疗前6个月和治疗后18个月 月（维护期）。 患者体内的个体部位为 根据它们的初始探测袋深度值分类：浅、中等 或者很深 治疗和维持效果通过使用 联合使用多变量统计方法（Hotelling T方检验），以及 每一类网站，分别。 对于该数据集，表明这种保守疗法产生了 深度部位有显著改善，中度部位有轻微改善 场地，以及浅层场地的严重退化。