STATISTICAL ISSUES FOR GINGIVITIS TRIALS OF SUPERIORITY AND EQUIVALENCE

牙龈炎优效性和等效性试验的统计问题

• 批准号: 3875289
• 负责人: A KINGMAN
• 金额: --
• 依托单位: NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3875289
• 关键词: clinical trials; gingivitis; human therapy evaluation; statistics /biometry

The purpose of this study is to present and discuss statistical issues as they arise in the design and analysis of gingivitis clinical trials demonstrating either superiority or equivalence. The problems of designing and interpreting data that are obtained from an equivalence trial are being investigated. There are a variety of statistical issues that are important when conducting studies in which no bona fide control or placebo group is included. Their implications for gingivitis studies will be the focus of this study.

本研究的目的是提出和讨论统计问题， 它们出现在牙龈炎临床试验的设计和分析中， 证明优效性或等效性。设计问题 并解释从等效性试验中获得的数据， 研究了有很多重要的统计问题 当进行没有真正的对照组或安慰剂组的研究时， 包括.它们对牙龈炎研究的影响将是 本研究