课题基金 / 基金详情

DEGRADATION OF EXTRACELLULAR MATRIX IN HUMAN GLOMERULI

DEGRADATION OF EXTRACELLULAR MATRIX IN HUMAN GLOMERULI
人肾小球细胞外基质的降解
批准号：
3840311
负责人：
L J STRIKER
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3840311
关键词：
basement membrane cellular pathology collagen complementary DNA dissection extracellular glomerulonephritis human tissue molecular pathology nephrectomy polymerase chain reaction protein degradation renal glomerulus

项目摘要

项目成果

L J STRIKER的其他基金

相似基金

相关文献

中文摘要
翻译
肾小球中胶原和非胶原成分的降解
英文摘要
Degradation of collagens and non-collagenous components of the glomerular extracellular matrix is believed to play an important role in the turnover of normal glomerular basement membranes, and in the pathogenesis of glomerulosclerosis. A new method combining microdissection of human glomeruli and competitive PCR has been utilized to examine glomeruli isolated from nephrectomy specimens. This method allows the detection of cDNA molecules in individual glomeruli, because of a detection range in the range of 10-4 attomoles. Preliminary results from glomeruli isolated from human nephrectomies indicate that the method is sensitive, reproducible, and allows comparison between patients.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
PRODUCTION OF METALLOPROTEINASES AND TIMPS BY GLOMERULAR CELLS
GLOMERULAR LESIONS IN NON-OBESE DIABETIC MICE
PRODUCTION OF METALLOPROTEINASES AND TIMPS BY GLOMERULAR CELLS
GLOMERULAR LESIONS IN NON-OBESE DIABETIC MICE
海外基金