Standing up for Dementia: exchanging knowledge on developing a patient and professional pathway for physical activity and exercise.
Standing up for Dementia: exchanging knowledge on developing a patient and professional pathway for physical activity and exercise.
批准号:
ES/K007688/1
负责人:
Michael Trenell
金额:
$12.8万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2013
资助国家:
英国
项目状态:
已结题
起止时间:
2013 至 --
中文摘要
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英文摘要
Dementia is currently a major healthcare problem. As our population ages, the number of people suffering from dementia increases yearly. This comes at both a large human and financial cost. Currently, there is no cure for dementia but medication can help to delay the progress of the disease although this has varying degrees of success - other treatment options which involve the patient more directly in their own care are therefore a necessity. Mild cognitive impairment (MCI - defined as a level of cognitive impairment which although noticeable, does not impact sufficiently on an individual's life to be diagnosed as dementia) is seen a stepping stone in the development of dementia, with large numbers of people diagnosed going on to develop dementia over the coming years. One of the main symptoms of dementia and MCI is the detrimental effect that it has on cognitive processes (for example memory, planning, perception and orientation). Within an elderly age group, research suggests that increasing physical activity can have beneficial effects on cognitive processes in later life and this may also be the case in individuals with MCI. This can also be protective as people who are more physically active in their younger years are at less risk of developing dementia as they get older. Unfortunately, many of the studies carried out so far in groups with MCI have not been performed to a high methodological standard, often with mixed groups of dementia participants with different diagnoses of dementia (it is likely that different types of dementia will respond differently to physical activity, just as they do with medications prescribed), in different care settings and without comparable cognitive assessment tools. This means that there is no current clinical advice for individuals with MCI, their caregivers and healthcare professionals as to what sort of physical activity may be beneficial to them as an alternative to current treatments. We propose to develop a behaviour change program which promotes the use of physical activity to maintain cognitive function and prevent cognitive decline in older adults at risk of dementia (those with MCI). This will aim to change the behaviour of both the individual with MCI and the healthcare professionals responsible for their care with the ultimate aim that physical activity can be offered as a healthcare 'prescription' to individuals.
期刊论文(10)
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Muscle Sympathetic Nerve Activity Is Associated with Liver Insulin Sensitivity in Obese Non-Diabetic Men.
肥胖非糖尿病男性的肌肉交感神经活动与肝脏胰岛素敏感性相关。
DOI:
10.3389/fphys.2017.00101
发表时间:
2017
期刊:
Frontiers in physiology
影响因子:
4
作者:
[Chen DL, Brown R, Liess C, Poljak A, Xu A, Zhang J, Trenell M, Jenkins A, Chisholm D, Samocha-Bonet D, Macefield VG, Greenfield JR]
通讯作者:
Greenfield JR
DOI:
10.1371/journal.pone.0187982
发表时间:
2017
期刊:
PloS one
影响因子:
3.7
作者:
[Cassidy S, Trenell MI, Anderson KN]
通讯作者:
Anderson KN
DOI:
10.1007/s00125-016-4106-1
发表时间:
2017-01
期刊:
Diabetologia
影响因子:
8.2
作者:
[Cassidy S, Thoma C, Houghton D, Trenell MI]
通讯作者:
Trenell MI
DOI:
10.1186/s12966-017-0514-y
发表时间:
2017-04-28
期刊:
The international journal of behavioral nutrition and physical activity
影响因子:
--
作者:
[Cassidy S, Chau JY, Catt M, Bauman A, Trenell MI]
通讯作者:
Trenell MI
DOI:
10.1186/s13012-016-0459-6
发表时间:
2016-07-19
期刊:
Implementation science : IS
影响因子:
--
作者:
[Avery L, Charman SJ, Taylor L, Flynn D, Mosely K, Speight J, Lievesley M, Taylor R, Sniehotta FF, Trenell MI]
通讯作者:
Trenell MI
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