Life Study: core scientific leadership and management team

生命研究：核心科学领导和管理团队

• 批准号: ES/L002353/1
• 负责人: Carol Dezateux
• 金额: $ 745.84万
• 依托单位: University College London
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2013
• 资助国家: 英国
• 起止时间: 2013 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=ES%2FL002353%2F1
• 关键词: Life; Study; core; scientific; leadership

A birth cohort study follows the same babies throughout their lives to understand more about how a child's very early social, emotional and physical development and their family and wider environment influences their future development, health and wellbeing as well as their risk of future ill health. These special types of studies give insights into what is called the life course starting in early life - they are a unique and special way to find out how early life experiences matter for later childhood and adult life. Our study will help identify what aspects of the environment in its broadest sense protect children and maximise their life chances and the ways in which that protection operates. It will also help us understand what aspects may increase vulnerability. We wish to understand the interplay between environmental and biological influences in early life recognising that this needs understanding of parents' lives and the wider family and society too.We will invite more than 100,000 pregnant women and their partners from across the UK to join our study. We want to include women and their partners from all walks of life. We will work to maximise recruitment of people from different ethnic groups. In pregnancy both parents will be interviewed, weighed and measured and asked to take part in some simple computer based tests. Parents will be asked to bring their baby to be seen at 6 and 12 months of age for some body size measurements and eye and child development tests. There will be no blood tests for the baby. We hope to follow all the children and their families throughout childhood and adult life so that we can see how they grow and develop and how their family circumstances change. We will do that in a number of ways including by getting consent at the beginning of the study to link to future routine health and other records of the baby and the parent. Scientists and others learn a lot from these large studies about how we can help children get a good start in life and improve their life chances and future well being and happiness. The information collected will be anonymised and made available to researchers to analyse to make sure we get the most benefit from it. We will be able to compare the Life Study generation with information collected from earlier generations in similar special British cohort studies.We will make sure that families taking part are informed about the progress of the study and any early findings and will ensure that other scientists, in the UK and abroad, policymakers and all members of the public also get to hear about Life Study findings.

一项出生队列研究跟踪了同一批婴儿的一生，以更多地了解儿童早期的社会，情感和身体发育以及他们的家庭和更广泛的环境如何影响他们未来的发展，健康和福祉以及他们未来健康不良的风险。这些特殊类型的研究让我们深入了解从生命早期开始的所谓生命历程-它们是一种独特而特殊的方式，可以发现早期生活经历对后来的童年和成年生活的重要性。我们的研究将有助于确定环境的哪些方面在最广泛的意义上保护儿童，最大限度地提高他们的生活机会，以及保护工作的方式。它还将帮助我们了解哪些方面可能增加脆弱性。我们希望了解生命早期环境和生物影响之间的相互作用，认识到这需要了解父母的生活以及更广泛的家庭和社会。我们将邀请来自英国各地的10万多名孕妇及其伴侣参加我们的研究。我们希望包括各行各业的妇女及其伴侣。我们将努力最大限度地从不同种族群体中招聘人员。在怀孕期间，父母双方将接受采访，称重和测量，并要求参加一些简单的基于计算机的测试。父母将被要求在6个月和12个月大的时候带着他们的婴儿去做一些身体尺寸测量和眼睛和儿童发育测试。不会对婴儿进行血液检查。我们希望在整个童年和成年生活中跟踪所有儿童及其家庭，以便我们可以看到他们如何成长和发展，以及他们的家庭环境如何变化。我们将通过多种方式做到这一点，包括在研究开始时获得同意，以链接到婴儿和父母未来的常规健康和其他记录。科学家和其他人从这些大型研究中学到了很多关于我们如何帮助孩子们在生活中有一个良好的开端，改善他们的生活机会和未来的幸福和幸福。收集到的信息将被匿名化，并提供给研究人员进行分析，以确保我们从中获得最大的利益。我们将能够将生命研究一代与类似的特殊英国队列研究中从前几代收集的信息进行比较。我们将确保参与研究的家庭了解研究的进展和任何早期发现，并确保其他科学家，在英国和国外，政策制定者和所有公众成员也可以听到生活研究的结果。

项目成果

Life Study Standard Operating Procedures: Adult Anthropometry

生命研究标准操作程序：成人人体测量

• DOI: 10.14324/000.wp.1485682
• 作者: Dezateux C

Life Study Birth Component Participant Materials

生命研究出生部分参与者材料

• DOI: 10.14324/000.wp.1485686
• 作者: Dezateux C

Life Study Birth component mother consent form

生命研究出生成分母亲同意书

• DOI: 10.14324/000.wp.1485690
• 作者: Dezateux C

Life Study Pregnancy component father/partner consent form

生命研究怀孕部分父亲/伴侣同意书

• DOI: 10.14324/000.wp.1485704
• 作者: Dezateux C

Life Study Communication and Engagement Strategy

生活研究沟通和参与策略

• DOI: 10.14324/000.rp.1485683
• 作者: Clohessy L