The Northern Ireland Cohort for the Longitudinal Study of Ageing (NICOLA) - CAPI

北爱尔兰老龄化纵向研究队列 (NICOLA) - CAPI

• 批准号: ES/L008459/1
• 负责人: Frank Kee
• 金额: $ 343.25万
• 依托单位: Queen's University Belfast
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2013
• 资助国家: 英国
• 起止时间: 2013 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=ES%2FL008459%2F1
• 关键词: Northern; Ireland; Cohort; Longitudinal; Study

The NICOLA study will be the most detailed study on ageing ever undertaken in Northern Ireland.NICOLA has been set up by a group of researchers in the Centre for Public Health in Queen's University Belfast. The purpose of NICOLA is to understand the health, lifestyles and financial situation of 8,500 people as they grow older in Northern Ireland, and to see how their circumstances change over a 10-15 year period as they move into and progress beyond retirement. The study will cover a broad set of topics relevant to a full understanding of the ageing process.The results will then be compared to those from similar studies in the United Kingdom and the Republic of Ireland.The study is important as the population aged over 50 is the most rapidly growing group in Northern Ireland.Not enough is known about the implications of population ageing. Until now there has not been good enough data to study the issues and therefore inform government policy on health, pensions or retirement, for example. Key questions that this study will be designed to answer are:What is the relationship between health and wealth?What determines the nature and timing of retirement?How important are household and family structures to health, wealth and quality of life?How adequate are financial provisions for retirement, and how can policy help?How should the government optimise the use and quality of health and social care services?What is the nature and structure of social networks, support and participation for older people?8500 people throughout Northern Ireland have been randomly selected to become members of this study. Study members and their partners will be interviewed in a Computer Assisted Personal Interview (CAPI) every two years in order to build up a detailed picture of how circumstances change in later life.The NICOLA study consists of the following 3 stages: an interview, a questionnaire and a health assessment. In this first stage, a 90 minute Computer Assisted Personal Interview (CAPI) is conducted in the participants own home at a time that suits them. IPSOS Mori, a leading research company, have been commissioned to carry out these home interviews.The interviewers collect information on living arrangements, children, education, income and assets, physical and mental health, employment, lifelong learning, planning for retirement, care and social support. They record this information using a computer. Questions will be asked about health, diet, work, family and social networks, income and benefit receipts, quality of life, cognitive functioning, daily activities, housing, retirement and pensions. The affect of 'the troubles' on the lives of people will also be explored.NICOLA study members further invited to take part in a home interview every two years and a health assessment every four years. All participants will be provided with detailed information sheets prior to the home interview and health assessment and will have the opportunity to contact the study team directly to ask any questions they may have.Information gathered during this study will be used to inform and plan Northern Ireland Health and Social Care provision in the future, and to design other policies targeted towards older people. Academic researchers will also use the data to help understand important questions in health, economics and ageing. Their results will then be used to advise policy makers on how best to design policies for health and pensions and to compare the Northern Ireland population to similar populations in other countriesEverything captured in the interview is treated in strict confidence. The results will not be used in any way in which they can be associated with participants or their addresses.All information you give will be treated in the strictest confidence and used for research purposes only.

NICOLA的研究将是北爱尔兰有史以来对老龄化进行的最详细的研究。NICOLA是由贝尔法斯特女王大学公共卫生中心的一组研究人员建立的。NICOLA的目的是了解北爱尔兰8,500人随着年龄增长的健康、生活方式和财务状况，并了解他们在进入退休和退休后的10-15年期间的情况如何变化。这项研究将涵盖与全面了解老龄化过程有关的一系列广泛主题。研究结果将与英国和爱尔兰共和国的类似研究结果进行比较。这项研究很重要，因为50岁以上的人口是北爱尔兰增长最快的群体。人们对人口老龄化的影响了解得还不够。到目前为止，还没有足够好的数据来研究这些问题，从而为政府的健康、养老金或退休等政策提供信息。这项研究将回答的关键问题是：健康和财富之间的关系是什么？是什么决定了退休的性质和时间？家庭和家庭结构对健康、财富和生活质量有多重要？退休后的财务准备是否足够？政策如何提供帮助？政府应如何优化卫生和社会保健服务的使用和质量？老年人的社会网络、支持和参与的性质和结构是什么？北爱尔兰的8500人被随机选择成为这项研究的成员。研究成员和他们的伴侣将每两年接受一次计算机辅助个人访谈（CAPI）的采访，以建立一个详细的画面，了解环境如何在以后的生活中发生变化。NICOLA研究包括以下3个阶段：访谈、问卷调查和健康评估。在第一阶段，一个90分钟的计算机辅助个人访谈（CAPI）在参与者自己的家中进行，在他们适合的时间。IPSOS Mori是一家领先的研究公司，已被委托进行这些家庭访谈。采访者收集有关生活安排、子女、教育、收入和资产、身心健康、就业、终身学习、退休计划、护理和社会支持等方面的资料。他们用电脑记录这些信息。问题将涉及健康、饮食、工作、家庭和社会网络、收入和福利收入、生活质量、认知功能、日常活动、住房、退休和养老金。“麻烦”对人们生活的影响也将被探讨。NICOLA进一步邀请研究成员参加每两年一次的家庭访谈和每四年一次的健康评估。在家访和健康评估之前，所有参与者都将获得详细的信息表，并有机会直接与研究团队联系，询问他们可能存在的任何问题。在这项研究期间收集的信息将用于为今后北爱尔兰的保健和社会保健提供信息和规划，并设计针对老年人的其他政策。学术研究人员还将利用这些数据来帮助理解健康、经济和老龄化方面的重要问题。然后，他们的调查结果将被用来为政策制定者提供建议，建议他们如何最好地设计健康和养老金政策，并将北爱尔兰的人口与其他国家的类似人口进行比较。结果将不会以任何方式使用，他们可以与参与者或他们的地址相关联。您提供的所有信息将被严格保密，并仅用于研究目的。

项目成果

A blood DNA methylation biomarker for predicting short-term risk of cardiovascular events.

• DOI: 10.1186/s13148-022-01341-4
• 发表时间: 2022-09-29
• 期刊: Clinical epigenetics
• 影响因子: 5.7

Genetic and epigenetic analysis in genes affecting mitochondrial function are associated with chronic kidney disease in an older population (oral presentation at Kidney Week 2018; abstract published in J Am Soc Nephrol)

影响线粒体功能的基因的遗传和表观遗传分析与老年人群中的慢性肾病相关（2018 年肾脏周口头报告；摘要发表在 J Am Soc Nephrol 上）

• 发表时间: 2018
• 作者: Cappa R

Genetic biomarkers in the over 40s in Northern Ireland: evidence from the Northern Ireland COhort of Longitudinal study of Ageing (NICOLA)

北爱尔兰 40 岁以上人群的遗传生物标志物：来自北爱尔兰老龄化纵向研究队列 (NICOLA) 的证据

• 发表时间: 2017
• 作者: Canadas Garre ML

Early key findings from a study of older people in Northern Ireland: The NICOLA Study: NICOLA: Key findings from Wave 1

对北爱尔兰老年人的一项研究的早期主要发现：NICOLA 研究：NICOLA：第一波的主要发现

• 发表时间: 2017
• 作者: Cruise Sharon

Water Dilutes and Alcohol Concentrates Urinary Arsenic Species When Food is the Dominant Source of Exposure

• DOI: 10.1007/s12403-019-00329-5
• 发表时间: 2019-11-05
• 期刊: EXPOSURE AND HEALTH
• 影响因子: 6.7
• 作者: de Moraes，Natalia V.;Carey，Manus;Meharg，Andrew A.
• 通讯作者: Meharg，Andrew A.