Defining Poly-C-binding protein/RNA complex antiviral targets.

定义 Poly-C 结合蛋白/RNA 复合物抗病毒靶点。

• 批准号: nhmrc : GNT1102718
• 负责人: A/Pr Jacqueline Wilce
• 金额: $ 59.7万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/defining-poly-c-antiviral-targets/1346235
• 关键词: Defining; Poly; binding; protein; RNA

This project investigates the way in which viruses are able to use host cell machinery to make viral proteins and to replicate their own genetic material. We focus on the picornavirus family that cause illnesses with important health and economic consequences including serious heart infections such as myocarditis and pericarditis as well as the 'common cold'. This research we will reveal new possible avenues of antiviral development.

该项目研究病毒如何能够利用宿主细胞机制来制造病毒蛋白质并复制自己的遗传物质。我们专注于小核糖核酸病毒家族，这些病毒引起的疾病具有重要的健康和经济后果，包括严重的心脏感染，如心肌炎和心包炎以及“普通感冒”。这项研究将揭示抗病毒药物开发的新的可能途径。